| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:DMPQ dihydrochloride;5,7-DiMethoxy-3-(4-pyridinyl)quinolinedihydrochloride
CAS:137206-97-4
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
SynAsst Chemical.
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| Tel: |
021-60343070 |
| Email: |
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| Products Intro: |
Product Name:5,7-DiMethoxy-3-(pyridin-4-yl)quinoline dihydrochloride
CAS:137206-97-4
Purity:96%Min Package:10g 100g 500g
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| Company Name: |
Synchem OHG
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| Tel: |
+49 5662 408730 |
| Email: |
info@synchem.de |
| Products Intro: |
Product Name:DMPQ Dihydrochloride;Quinoline, 5,7-dimethoxy-3-(4-pyridinyl)-
CAS:137206-97-4
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| Company Name: |
EMMX Biotechnology LLC
|
| Tel: |
888-539-0666 |
| Email: |
info@emmx.com |
| Products Intro: |
Product Name:DMPQ dihydrochloride
CAS:137206-97-4
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| | 5,7-DIMETHOXY-3-(4-PYRIDINYL)QUINOLINE DIHYDROCHLORIDE Basic information |
| | 5,7-DIMETHOXY-3-(4-PYRIDINYL)QUINOLINE DIHYDROCHLORIDE Chemical Properties |
| Boiling point | 441.3±40.0 °C(Predicted) | | density | 1.192±0.06 g/cm3(Predicted) | | storage temp. | Store at RT | | solubility | Soluble in DMSO (up to 1 mg/ml with warming) or in Water (up to 30 mg/ml). | | form | solid | | pka | 3.58±0.38(Predicted) | | color | Yellow | | Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 2 months. |
| | 5,7-DIMETHOXY-3-(4-PYRIDINYL)QUINOLINE DIHYDROCHLORIDE Usage And Synthesis |
| Description | DMPQ 2HCl (137206-97-4) is a potent and selective inhibitor of PDGFRβ, IC50=80 nM. Greater than 100-fold more selective compared to EGFR, erB2, p56, PKA and PKC. Cell permeable. | | Uses | DMPQ dihydrochloride is a selective an a potent inhibitor of human platelet-derived growth factor receptor β (PDGFRβ). | | Biological Activity | A potent and selective inhibitor of human vascular β -type platelet derived growth factor receptor tyrosine kinase (PDGFR β ) (IC 50 = 80 nM). Displays > 100-fold selectivity over EGFR tyrosine kinase, erbB2, p56, protein kinase A and protein kinase C. | | References | 1) Dolle et al. (1994), Effects of xanthine derivatives on lipolysis and on adenosine 3′,5′-monophosphate phosphodiesterase activity; J. Med. Chem., 37 2627 |
| | 5,7-DIMETHOXY-3-(4-PYRIDINYL)QUINOLINE DIHYDROCHLORIDE Preparation Products And Raw materials |
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