- ARP-100
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- $31.00 / 1mg
-
2024-11-19
- CAS:704888-90-4
- Min. Order:
- Purity: 98.24%
- Supply Ability: 10g
- ARP-100
-
- $31.00 / 1mg
-
2024-11-19
- CAS:704888-90-4
- Min. Order:
- Purity: 98.24%
- Supply Ability: 10g
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| | ARP100 Basic information | | Uses |
| Product Name: | ARP100 | | Synonyms: | ARP100;N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)acetamide;2-[((1,1'-Biphenyl)-4-ylsulfonyl)-(1-methylethoxy)amino]-N-hydroxyacetamide;MMP-2 Inhibitor III;N-hydroxy-2-[(4-phenylphenyl)sulfonyl-propan-2-yloxyamino]acetamide;Acetamide, 2-[([1,1'-biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-;N-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide;metalloproteinase,Inhibitor,Matrix metalloproteinases,selective,matrigel,ARP 100,matrix,invasion,ARP100,anti-invasive,MMP,ARP-100,inhibit | | CAS: | 704888-90-4 | | MF: | C17H20N2O5S | | MW: | 364.42 | | EINECS: | | | Product Categories: | | | Mol File: | 704888-90-4.mol |  |
| | ARP100 Chemical Properties |
| storage temp. | Desiccate at +4°C | | solubility | Soluble at 100mM in DMSO | | form | Solid | | color | Off-white to light yellow |
| | ARP100 Usage And Synthesis |
| Uses | ARP 100 is a potent, dual inhibitor of MMP-12/MMP-13 targets, which are a family of zinc dependent endopeptidases known to play key roles in extracellular matrix (ECM) breakdown disorders, such as the two main forms of arthritis, rheumatoid arthritis (RA) and osteoarthritis (OA). | | Uses | A selective inhibitor of MMP-2 | | Biological Activity | Selective inhibitor of MMP-2 (IC 50 = 12 nM); displays selectivity over MMP-9, MMP-3, MMP-1 and MMP-7 (IC 50 values are 200, 4500, > 50000 and > 50000 nM respectively). Exhibits anti-invasive properties in HT1080 fibrosarcoma cells. |
| | ARP100 Preparation Products And Raw materials |
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