Asocainol

Asocainol Suppliers list
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 18871490254
Email: linda@hubeijusheng.com
Products Intro: Product Name:Asocainol
CAS:77400-65-8
Purity:0.99 Package:5KG;1KG
Company Name: J & K SCIENTIFIC LTD.  
Tel: 010-82848833 400-666-7788
Email: jkinfo@jkchemical.com
Products Intro: Product Name:Asocainol
CAS:77400-65-8
Package:2.5Mg,25Mg
Company Name: Chemsky (shanghai) International Co.,Ltd  
Tel: 021-50135380
Email: shchemsky@sina.com
Products Intro: Product Name:Asocainol
CAS:77400-65-8
Purity:98+% Package:1Mg;5Mg;10Mg;50Mg;100Mg;500Mg
Company Name: Shenzhen Polymeri Biochemical Technology Co., Ltd.  
Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Products Intro: Product Name:Asocainol
CAS:77400-65-8
Company Name: Hubei huizepu Pharmaceutical Technology Co., Ltd  
Tel: 027-19371-3712 19371278702
Email: n17762444226@163.com
Products Intro: Product Name:5H-Dibenz[d,f]azonin-1-ol,6,7,8,9-tetrahydro-2,12-dimethoxy-7-methyl-6-(2-phenylethyl)-
CAS:77400-65-8
Asocainol Basic information
Product Name:Asocainol
Synonyms:Asocainol;6,7,8,9-Tetrahydro-2,12-dimethoxy-7-methyl-6-(2-phenylethyl)-5H-dibenz[d,f]azonin-1-ol;Go-4704;Goe-4704;5H-Dibenz[d,f]azonin-1-ol, 6,7,8,9-tetrahydro-2,12-dimethoxy-7-methyl-6-(2-phenylethyl)-
CAS:77400-65-8
MF:C27H31NO3
MW:417.54
EINECS:
Product Categories:Aromatics;Heterocycles;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals
Mol File:77400-65-8.mol
Asocainol Structure
Asocainol Chemical Properties
Safety Information
MSDS Information
Asocainol Usage And Synthesis
OriginatorAsocainol,ZYF Pharm
UsesAsocainol (ASOC) belongs to class I antiarrhythmic drugs, i.e., those that exert their action at the level of sodium channels of the myocardial cell membrane.
UsesLabelled Asocainol
Manufacturing ProcessA solution of a Grignard reagent is prepared from 5.5 g (0.23 mol) activated magnesium turnings and 41.5 g (0.24 mol) phenethyl bromide in 200 ml anhydrous diethyl ether. To this is added dropwise, at 35-40°C, a solution of 31.5 g (0.1 mol) thebaine in 0.4 liters dry benzene. After heating under reflux for 2 hours, the reaction mixture is decomposed with a solution of 48 g ammonium chloride in 200 ml water. The usual working up, after conversion of the base into the hydrochloride by means of hydrogen chloride in ethyl acetate, gives 7.3 g (21% of theory) (+/-)-2,12-dimethoxy-1-hydroxy-7- methyl-6-phenethyl-5,6,8,9-tetrahydro-7H-dibenz[d,f]azonine hydrochloride, melting point 227.6°C, after recrystallization from propan-2-ol.
Therapeutic FunctionAntiarrhythmic
Asocainol Preparation Products And Raw materials
Raw materialsTHEBAINE-->(2-Bromoethyl)benzene-->Ammonium chloride
Tag:Asocainol(77400-65-8) Related Product Information
CHEMBRDG-BB 5535468 Asocainol

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