| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:Acifran;4,5-Dihydro-5-Methyl-4-oxo-5-phenyl-2-furancarboxylicacid
CAS:72420-38-3
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
EMMX Biotechnology LLC
|
| Tel: |
888-539-0666 |
| Email: |
info@emmx.com |
| Products Intro: |
Product Name:Acifran
CAS:72420-38-3
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| | ACIFRAN Basic information |
| Product Name: | ACIFRAN | | Synonyms: | ay25712;ACIFRAN;4,5-DIHYDRO-5-METHYL-4-OXO-5-PHENYL-2-FURANCARBOXYLIC ACID;(R,S)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid;4,5-Dihydro-5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid;Acifranum;4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylicaci;5-Methyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxylic acid | | CAS: | 72420-38-3 | | MF: | C12H10O4 | | MW: | 218.21 | | EINECS: | | | Product Categories: | Miscellaneous Compounds | | Mol File: | 72420-38-3.mol |  |
| | ACIFRAN Chemical Properties |
| Melting point | 176° | | Boiling point | 378.4±42.0 °C(Predicted) | | density | 1.343±0.06 g/cm3(Predicted) | | storage temp. | Store at +4°C | | solubility | Soluble in DMSO > 10 mM | | form | Powder | | pka | 2.25±0.40(Predicted) | | color | Off-white to light yellow |
| Toxicity | LD50 orally in rats: 3 g/kg (Jirkovsky, 1982) |
| | ACIFRAN Usage And Synthesis |
| Uses | Antihyperlipopro-teinemic. | | Uses | Acifran is a nicotinic acid receptor agonist. | | Brand name | Reductol (Wyeth-Ayerst). | | Biological Activity | Hypolipidaemic agent; more potent than nicotinic acid and clofibrate. Full and potent agonist at the human orphan GPCR HM74A/GPR109A and GPR109B (EC 50 values are 1.3? and 4.2 μ M respectively). In vivo, reduces serum triglycerides and circulating LDL-cholesterol without affecting liver weight or liver enzymes. | | storage | Store at +4°C |
| | ACIFRAN Preparation Products And Raw materials |
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