ascamycin
中文名称 | ascamycin |
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中文同义词 | 阿斯卡霉素;化合物 T14329;化合物ASCAMYCIN |
英文名称 | ascamycin |
英文同义词 | ascamycin;(+)-5'-O-[[(S)-2-Amino-1-oxopropyl]aminosulfonyl]-2-chloroadenosine;2-Chloro-5'-O-[(L-alanylamino)sulfonyl]adenosine;2-Chloro-5'-O-[[(S)-2-amino-1-oxopropyl]sulfamoyl]adenosine |
CAS号 | 91432-48-3 |
分子式 | |
分子量 | 0 |
EINECS号 | |
相关类别 | |
Mol文件 | 91432-48-3.mol |
结构式 | ![]() |
ascamycin 性质
MIC: 0.4 μg/mL ( Xanthomonas citri ), 12.5 μg/mL ( Xanthomonas oryzae ) and 12.5 μg/mL ( Mycobacterium phlei )
The Ascamycin has C2-chloroadenine as the base on C-1' which lacks the chlorine. Ascamycin has a selective antibacterial activity against Xanthomonas species. When Ascamycin is dealanylated, Dealanylascamycin shows a broad antibacterial activity against various Gram-negative and Gram-positive bacteria. Xanthomonas citri is susceptible to Ascamycin by virtue of the Ascamycin-dealanylating enzyme on the cell surface.