异隐丹参酮
中文名称 | 异隐丹参酮 |
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中文同义词 | 异隐丹参酮;异丹参酮 III |
英文名称 | (8S)-1,2,3,4,8,9-Hexahydro-4,4,8-trimethylphenanthro[3,2-b]furan-7,11-dione |
英文同义词 | (+)-1,2,3,4,8,9-Hexahydro-4,4,8-trimethylphenanthro[3,2-b]furan-7,11-dione;(8S)-1,2,3,4,8,9-Hexahydro-4,4,8-trimethylphenanthro[3,2-b]furan-7,11-dione;Isotanshinone III;Isocryptotanshinone;Phenanthro[3,2-b]furan-7,11-dione, 1,2,3,4,8,9-hexahydro-4,4,8-trimethyl-, (8S)- |
CAS号 | 22550-15-8 |
分子式 | C19H20O3 |
分子量 | 296.36 |
EINECS号 | |
相关类别 | 中药对照品;标准品 -中药标准品 |
Mol文件 | 22550-15-8.mol |
结构式 |
异隐丹参酮 性质
储存条件 | Store at -20°C |
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溶解度 | 溶于氯仿、二氯甲烷、乙酸乙酯、DMSO、丙酮等。 |
形态 | 粉末 |
STAT3
|
PTP1B 56.1 μM (IC 50 ) |
It is showed that tanshinones significantly inhibited A549 proliferation and Isocryptotanshinone (ICTS) exhibits the strongest activity. Isocryptotanshinone inhibits the constitutive STAT3 and p-STAT3 (Y705) expression in concentration and time-dependent manners. Isocryptotanshinone dramatically inhibits the IL-6-stimulated expression of p-STAT3 (Y705) in a time-dependent manner.