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| CONANTOKIN G Basic information |
| CONANTOKIN G Chemical Properties |
RTECS | GK5900000 | storage temp. | −20°C | form | Solid | Water Solubility | Soluble in water at 1mg/ml |
| CONANTOKIN G Usage And Synthesis |
Uses | Non-competitive inhibitor of NMDA glutamatergic receptors acting at the polyamine site. Conantokin G (CGX-1007), a member of the conantokin family, is a selective NR2B subunit inhibitor of NMDA glutamatergic receptors with activity as a neuroprotective agent against NMDA-induced excitotoxicity. | General Description | The most selective and potent non-competitive antagonist among the members of the conantokin peptide family for NR2B-containing NMDAR channels (Ki = 0.8 μM with close to 100% inhibition of NR1/NR2B mediated current). Widely used for studies related to NMDAR neurotransmissions in both peripheral and center nervous systems. | Biochem/physiol Actions | Primary TargetNMDA receptors |
| CONANTOKIN G Preparation Products And Raw materials |
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Tag:CONANTOKIN G(93438-65-4)
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