UK-37248
中文名称 | UK-37248 |
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中文同义词 | 盐酸达唑苄;盐酸达唑氧苯;化合物UK-37248;4-(2-(1H-咪唑-1-基)乙氧基)苯甲酸盐酸盐 |
英文名称 | UK-37248 |
英文同义词 | Dazoxiben hydrochloride;UK-37248;UK-37248-01;4-(2-(1H-Imidazol-1-yl)ethoxy)benzoic acid hydrochloride;Dazoxiben HCl;Dazoxiben,Inhibitor,inhibit |
CAS号 | 74226-22-5 |
分子式 | C12H13ClN2O3 |
分子量 | 268.69622 |
EINECS号 | |
相关类别 | |
Mol文件 | 74226-22-5.mol |
结构式 | ![]() |
UK-37248 性质
熔点 | 230-235 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7)) |
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储存条件 | under inert gas (nitrogen or Argon) at 2-8°C |
溶解度 | DMSO:58.0(最大浓度 mg/mL);215.86(最大浓度 mM) |
Target | Value |
PGE2
() | |
TXB2
(Cell-free assay) | 0.3 μM |
Dazoxiben inhibits TXB2 production in clotting human whole blood with an IC 50 of 0.3 μM and causes parallel enhancement of PGE2 greater than PGF2 alpha greater than 6-keto-PGF1 alpha production. Dazoxiben inhibits TXB2 production in rat kidney glomeruli with an IC 50 of 1.60 μM) than in rat whole blood (IC 50 = 0.32μM), and is not associated with changes in PGE2, PGF2 alpha and 6-keto-PGF1 alpha production.
Dazoxiben (intraperitoneal administration; 100 μg/kg) produces a marked prolongation of the tail bleeding time with 96.8 ± 10.8 secs.
安全信息
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
---|---|---|---|---|---|
2024/04/30 | S0541 | UK-37248 Dazoxiben hydrochloride | 74226-22-5 | 5mg | 1168.08元 |
2024/04/30 | S0541 | UK-37248 Dazoxiben hydrochloride | 74226-22-5 | 25mg | 3976.74元 |