- LIXIVAPTAN
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- $36.00 / 1mg
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2024-11-19
- CAS:168079-32-1
- Min. Order:
- Purity: 98.36%
- Supply Ability: 10g
- LIXIVAPTAN
-
- $1.00 / 1KG
-
2019-12-26
- CAS:168079-32-1
- Min. Order: 1KG
- Purity: 97%-99.9%
- Supply Ability: 100kg
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| | LIXIVAPTAN Basic information |
| Product Name: | LIXIVAPTAN | | Synonyms: | LIXIVAPTAN;N-[3-Chloro-4-(5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-ylcarbonyl)phenyl]-5-fluoro-2-methylbenzamide;VPA 985;BenzaMide,N-[3-chloro-4-(5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-ylcarbonyl)phenyl]-5-fluoro-2-Methyl-;N-[3-Chloro-4-(5H-pyrrolo[2,1-c][1,4]benzodiazepine-10(11H)-ylcarbonyl)phenyl]-5-fluoro-2-methylbenzamide;N-[3-chloro-4-(6,11-dihydropyrrolo[2,1-c][1,4]benzodiazepine-5-carbonyl)phenyl]-5-fluoro-2-methyl-benzamide;Lixivaptan (VPA-985);VPA985;LIXIVAPTAN (VPA 985) | | CAS: | 168079-32-1 | | MF: | C27H21ClFN3O2 | | MW: | 473.93 | | EINECS: | | | Product Categories: | Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 168079-32-1.mol |  |
| | LIXIVAPTAN Chemical Properties |
| Melting point | >114°C (dec.) | | Boiling point | 626.5±55.0 °C(Predicted) | | density | 1.32 | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMSO: soluble20mg/mL, clear | | form | powder | | pka | 11.86±0.70(Predicted) | | color | white to beige | | InChIKey | PPHTXRNHTVLQED-UHFFFAOYSA-N |
| | LIXIVAPTAN Usage And Synthesis |
| Uses | Lixivaptan is a drug used in the treatment and prevention of cardiovascular diseases. | | Biological Activity | Arginine vasopressin (AVP) plays an important part in circulatory and water homoeostasis and is important in renal hemodynamic alterations, water retention, and cardiac remodeling in congestive heart failure (CHF). Lixivaptan is an AVP V2-receptor selective antagonist th at increases water excretion and normalizes serum sodium levels. Lixivaptan has been in clinical trials for hyponatremia associated with heart failure. |
| | LIXIVAPTAN Preparation Products And Raw materials |
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