| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:ACV 1
CAS:740980-24-9
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
Creative Peptides
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| Tel: |
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| Email: |
info@creative-peptides.com |
| Products Intro: |
Product Name:ACV 1
CAS:740980-24-9
Purity:>98% Package:1g; 10g;100g;1kg Remarks:Peptide Inhibitors
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| Company Name: |
Hangzhou Peptidego Biotech Co.,Ltd.
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| Tel: |
0571-87213919 |
| Email: |
eric@peptidego.com |
| Products Intro: |
Product Name:ACV1
CAS:740980-24-9
Purity:95% or 98% HPLC Package:1mg；5mg；10mg；50mg；100mg,1g or according to customer's detail requirement.
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| Company Name: |
BOC Sciences
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| Tel: |
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| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:ACV 1
CAS:740980-24-9
Purity:≥98% by HPLC Remarks:ACV 1 has been found to be a neuronal nicotinic receptor antagonist and could probably alleviate neuropathic pain.
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| Product Name: | ACV 1 | | Synonyms: | ACV 1;GLY-CYS-CYS-SER-ASP-PRO-ARG-CYS-ASN-TYR-ASP-HIS-PRO-GLU-ILE-CYS-NH2 | | CAS: | 740980-24-9 | | MF: | C71H103N23O25S4 | | MW: | 1806.99 | | EINECS: | | | Product Categories: | | | Mol File: | 740980-24-9.mol |  |
| | ACV 1 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder |
| | ACV 1 Usage And Synthesis |
| Enzyme inhibitor | This neuronal nicotinic acetylcholine receptor antagonist (FW = 1806.98 g/mol; CAS 740980-24-9), also known as Conotoxin Vc1.1, is produced from mRNA in venom duct of Conus victoriae. ACV 1 selectively targets the α9α10 nAChR subtype (IC50 = 19 nM), with weaker action against α6/α3β2β3 (IC50 = 140 nM), α6/α3β4 (IC50 = 980 nM), α3β4 (IC50 = 4200 nM), and α3β2 (IC50 = 7300 nM) nAChR subtypes. ACV-1 suppresses vascular responses to unmyelinated sensory nerve C-fiber activation in rats, as related to pain transmission. ACV-1 and its posttranslationally modified analogues vc1a, [P6O]Vc1.1, and [E14g]Vc1.1 are equally potent at inhibiting ACh-evoked currents mediated by α9α10 nAChRs. |
| | ACV 1 Preparation Products And Raw materials |
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