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| | (1-Methyl-1H-[1,2,4]triazol-3-yl)-methanol Basic information |
| Product Name: | (1-Methyl-1H-[1,2,4]triazol-3-yl)-methanol | | Synonyms: | (1-Methyl-1H-[1,2,4]triazol-3-yl)-methanol;1H-1,2,4-Triazole-3-methanol, 1-methyl-;1-Methyl-3-hydroxymethyl-1H-1,2,4-triazole;(1-Methyl-1H-[1,2,4]Triazol-3-yl)-Methanol,>95%;1-methyl-1H-1,2,4-Triazole-3-methanol;1-methyl-1,2,4-triazol-3-yl)methanol;3-(HYDROXYMETHYL)-1-METHYL-1H-1,2,4-TRIAZOLE;(1-METHYL-1H-1,2,4- TRIAZOLE -3-YL)METHANOL | | CAS: | 135242-93-2 | | MF: | C4H7N3O | | MW: | 113.12 | | EINECS: | | | Product Categories: | 1H-Inden-1-ol | | Mol File: | 135242-93-2.mol | ![(1-Methyl-1H-[1,2,4]triazol-3-yl)-methanol Structure](CAS2/GIF/135242-93-2.gif) |
| | (1-Methyl-1H-[1,2,4]triazol-3-yl)-methanol Chemical Properties |
| Boiling point | 296.8±42.0 °C(Predicted) | | density | 1.33±0.1 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | pka | 13.16±0.10(Predicted) | | InChI | InChI=1S/C4H7N3O/c1-7-3-5-4(2-8)6-7/h3,8H,2H2,1H3 | | InChIKey | WEDYTSQNYJKOPC-UHFFFAOYSA-N | | SMILES | N1(C)C=NC(CO)=N1 |
| HazardClass | IRRITANT | | HS Code | 2933998090 |
| | (1-Methyl-1H-[1,2,4]triazol-3-yl)-methanol Usage And Synthesis |
| Synthesis | 153.1 g (0.443 mol, 1.0 eq) of N-formyl-2-trityloxyacetamide was added to a 1L three-necked flask with a mechanical stirrer and a thermometer.30.6 g (0.664 mol, 1.5 eq) of methyl hydrazine and 800 mL of chloroform, stirring was started, 1.5 g (8.9 mmol, 0.02 eq) of p-toluenesulfonic acid was added, and the mixture was stirred at room temperature for 4 h. The remaining material in the HPLC control was less than 1 per cent.225mL2mol/L hydrochloric acid, stirring at room temperature for 2 hours, saturated sodium carbonate solution to adjust the pH value of 6-7, layering, the aqueous layer extracted with chloroform(100mL×2), the organic layer was combined with the solvent under reduced pressure to obtain a crude product. The crude product was recrystallized from ethanol/water (1:2), suction-filtered and dried.Colorless needle crystals (1-methyl-1H-[1,2,4]triazol-3-yl)-methanol 43.0 g, yield 85percent, purity 97.0percent (HPLC),Mp 73-75°C. |
| | (1-Methyl-1H-[1,2,4]triazol-3-yl)-methanol Preparation Products And Raw materials |
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