| Company Name: |
Lynnchem
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86-(0)29-85992781 17792393971 |
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info@lynnchem.com |
| Products Intro: |
Product Name:Bischloroanthrabenzoxocinone
CAS:866022-28-8
Purity:>99% by HPLC Package:0.5mg;2.5mg
|
| Company Name: |
Novachemistry
|
| Tel: |
44-20819178-90 02081917890 |
| Email: |
info@novachemistry.com |
| Products Intro: |
Product Name:Bischloroanthrabenzoxocinone
CAS:866022-28-8
Purity:>99% by HPLC Package:0.5mg;2.5mg
|
| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:Bischloroanthrabenzoxocinone
CAS:866022-28-8
Purity:>98% Package:1mg;10mg;50mg;100mg;
|
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| | Bischloroanthrabenzoxocinone Basic information |
| Product Name: | Bischloroanthrabenzoxocinone | | Synonyms: | Bischloroanthrabenzoxocinone;BABX;6,16-Epoxy-14H-anthra[2,3-d][1]benzoxocin-14-one, 10,12-dichloro-6,7,9,16-tetrahydro-11,13,15-trihydroxy-3-methoxy-1,6,9,9-tetramethyl-, (6R,16R)- | | CAS: | 866022-28-8 | | MF: | C28H24Cl2O7 | | MW: | 543.392 | | EINECS: | | | Product Categories: | Antibiotic | | Mol File: | 866022-28-8.mol |  |
| | Bischloroanthrabenzoxocinone Chemical Properties |
| Melting point | 167-169 °C(Solv: nitromethane (75-52-5)) | | Boiling point | 660.1±55.0 °C(Predicted) | | density | 1.475±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | | pka | 4.60±0.60(Predicted) |
| | Bischloroanthrabenzoxocinone Usage And Synthesis |
| Uses | Bischloroanthrabenzoxocinone ((-)BABX) is a selective inhibitor of Type II fatty acid synthesis (FASII). BABX showed IC50 values of 11.4 and 35.3 μg/ml in the S. aureus and E. coli FASII assays, respectively, with comparable antibacterial activities. Type II fatty acid synthesis (FASII) is essential to bacterial cell viability and is a promising target for the development of novel antibiotics. More recently, BABX has been shown to inhibit agonist binding to Liver X receptors (LXR). The receptors regulate the expression of the ABCA1 gene, which mediates the efflux of cholesterol from cells. |
| | Bischloroanthrabenzoxocinone Preparation Products And Raw materials |
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