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| | CP 945598 hydrochloride Basic information |
| Product Name: | CP 945598 hydrochloride | | Synonyms: | 1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic acid amide hydrochloride;CP-945598 HCl, >=99%;CP 945598 hydrochloride;1-[8-(2-Chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-
4-(ethylaMino)-4-piperidinecarboxaMide Monohydrochloride;1-[8-(2-Chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylaMino)-4-piperidinecarboxaMide Hydrochloride;CP 945;4-PiperidinecarboxaMide, 1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylaMino)-, (Hydrochloride) (1:1);Otenabant (Hydrochloride) | | CAS: | 686347-12-6 | | MF: | C25H26Cl3N7O | | MW: | 546.87924 | | EINECS: | | | Product Categories: | Inhibitors;Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pfizer Compounds;Pharmaceuticals | | Mol File: | 686347-12-6.mol |  |
| | CP 945598 hydrochloride Chemical Properties |
| Melting point | 275-276℃ (decomposition) | | storage temp. | room temp | | solubility | DMSO: soluble1mg/mL, clear (warmed) | | form | powder | | color | white to beige |
| | CP 945598 hydrochloride Usage And Synthesis |
| Chemical Properties | Off-White Solid | | Uses | CP 945598 is a selective, high affinity CB1 antagonist (Ki values are 0.7 and 0.12 nM in binding and functional assays respectively). Displays low affinity for CB2 receptors (Ki = 7600 nM). | | Biological Activity | CP-945,598 is a potent, selective, high affinity and competitive cannabinoid type 1 (CB1) receptor antagonist. CP-945,598 inhibits both basal and cannabinoid agonist-mediated CB1 receptor signaling in vitro and in vivo. CP-945,598 exhibits anorectic activity in two models of acute food intake in rodents, fast-induced re-feeding and spontaneous, nocturnal feeding.', 'CP-945,598 is also known as 1-(8-(2-Chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl)-4-(ethylamino)piperidine-4-carboxamide. This orally active antagonist of the cannabinoid CB-1 receptor may be used in the treatment of obesity. | | storage | Store at +4°C |
| | CP 945598 hydrochloride Preparation Products And Raw materials |
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