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Sigma-Aldrich
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021-61415566 800-8193336 |
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orderCN@merckgroup.com |
| Products Intro: |
Product Name:GTP-γ-S
CAS:37589-80-3
Purity:?% (GMP, HPLC); ?2% (GDP, HPLC); ?% (GTP, HPLC)
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| Company Name: |
Alfa Chemistry
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| Tel: |
1-516-6625404 |
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support@alfa-chemistry.com |
| Products Intro: |
Product Name:GTP-γ-S
CAS:37589-80-3
Purity:95% Package:1g;10g;100g;1KG;5KG
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| | GTP-GAMMA-S SODIUM SALT Basic information |
| Product Name: | GTP-GAMMA-S SODIUM SALT | | Synonyms: | GTP-GAMMA-S;GTP-GAMMA-S, NA;GTP-GAMMA-S SODIUM SALT;GUANOSINE-5'-(GAMMA-THIO)-TRIPHOSPHATE, SODIUM SALT;GUANOSINE-5'-[GAMMA-THIO]TRIPHOSPHATE TETRASODIUM SALT;GUANOSINE-5'-O-(3-THIOTRIPHOSPHATE) SODIUM SALT;GUANOSINE-5'-O-(3-THIOTRIPHOSPHORIC ACID), SODIUM;GTP-γ-S | | CAS: | 37589-80-3 | | MF: | C10H16N5O13P3S | | MW: | 539.25 | | EINECS: | | | Product Categories: | | | Mol File: | 37589-80-3.mol |  |
| | GTP-GAMMA-S SODIUM SALT Chemical Properties |
| density | 2.68±0.1 g/cm3(Predicted) | | storage temp. | -20°C (-15°C to -25°C) | | form | solution (deep frozen) | | pka | 0.67±0.50(Predicted) |
| | GTP-GAMMA-S SODIUM SALT Usage And Synthesis |
| Uses | GTP-γ-S has been used:
- in G-Protein activation assay to assess the functionality of protease-activated receptor 4 (PAR4)
- in fluorimetric guanine nucleotide exchange assay of G protein alpha subunits (Gα)
- to monitor the Rac family small guanosine triphosphatase (GTPase) 2 (Rac2)-stimulated activity of phospholipase Cγ2 mutants
| | Definition | ChEBI: Guanosine 5'-[gamma-thio]triphosphate is a nucleoside triphosphate analogue. It is functionally related to a GTP. | | General Description | Guanosine 5′-O-(3-thiotriphosphate), tetralithium salt (GTP-γ-S) is a non-hydrolysable analog of GTP. It is an inhibitor of phosphodiesterase in photoreceptors. | | Biochem/physiol Actions | Guanosine 5′-O-(3-thiotriphosphate) (GTP-γ-S) activates guanine-nucleotide-binding proteins and is slowly hydrolyzed enzymatically. It inhibits guanosine triphosphatase (GTPases) more potently than guanosine triphosphate (GTP), |
| | GTP-GAMMA-S SODIUM SALT Preparation Products And Raw materials |
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