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| | 1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Basic information |
| Product Name: | 1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one | | Synonyms: | 1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one;2-Propen-1-one, 1-[4-[2-[(4-chloro-2-hydroxy-5-iodophenyl)aMino]acetyl]-1-piperazinyl]-;K-Ras(G12C) inhibitor 12;1-[4-[2-[(4-chloro-2-hydroxy-5-iodophenyl)amino]acetyl]-1-piperazinyl]-2-propen-1-one;1-[4-[2-(4-chloro-2-hydroxy-5-iodoanilino)acetyl]piperazin-1-yl]prop-2-en-1-one k-ras(g12c)inhibitor6;K-Ras(G12C) inhibitor;K-Ras G12C-IN-12;105456 | | CAS: | 1469337-95-8 | | MF: | C15H17ClIN3O3 | | MW: | 449.67 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 1469337-95-8.mol |  |
| | 1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Chemical Properties |
| Boiling point | 680.2±55.0 °C(Predicted) | | density | 1.736±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | ≥8.98 mg/mL in DMSO with gentle warming | | pka | 8.60±0.50(Predicted) | | form | solid | | color | Off-white to light yellow |
| | 1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Usage And Synthesis |
| references | [1]. ostrem jm1, peters u, sos ml, et al. k-ras(g12c) inhibitors allosterically control gtp affinity and effector interactions. nature, 2013, 503(7477): 548-551. |
| | 1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Preparation Products And Raw materials |
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