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| | ACT 080803 Basic information |
| Product Name: | ACT 080803 | | Synonyms: | 5-(4-Bromo-phenyl)-6-[2-(5-bromo-pyrimidin-2-yloxy)-ethoxy]-pyrimidin-4-ylamine;5-(4-bromophenyl)-6-(2-((5-bromopyrimidin-2-yl);5-(4-Bromophenyl)-6-(2-((5-bromopyrimidin-2-yl)oxy)ethoxy)pyrimidin-4-amine;4-Pyrimidinamine, 5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-;Macitentan N-Despropylaminosulfonyl Impurity;Masitectan impurity;Macititan impurity 01;Macitentan Impurity 01 | | CAS: | 1433875-21-8 | | MF: | C16H13Br2N5O2 | | MW: | 467.11 | | EINECS: | | | Product Categories: | | | Mol File: | 1433875-21-8.mol |  |
| | ACT 080803 Chemical Properties |
| Boiling point | 607.5±65.0 °C(Predicted) | | density | 1.722±0.06 g/cm3(Predicted) | | solubility | DMSO (Slightly), Methanol (Slightly, Heated) | | pka | 3.00±0.10(Predicted) | | form | Solid | | color | White to Off-White |
| | ACT 080803 Usage And Synthesis |
| Uses | Despropylaminosulfonyl Macitentan is an impurity of Macitentan (M105005); a dual orally active endothelin receptor antagonist used for pulmonary arterial hypertension. |
| | ACT 080803 Preparation Products And Raw materials |
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