| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-KMT2D
Purity:Prestige Antibodies P Package:100μL Remarks:HPA035977
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| | Anti-MLL4 Basic information |
| Product Name: | Anti-MLL4 | | Synonyms: | Anti-KMS;Monoclonal Anti-MLL2 antibody produced in mouse;Anti-AKR1A1;Anti-Aldehyde Reductase antibody produced in goat;Anti-Aldo-keto reductase family 1;Anti-ALDR1;Anti-ERV1;Anti-GFER (76-90) antibody produced in rabbit | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![Anti-MLL4 Structure]() |
| | Anti-MLL4 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| | Anti-MLL4 Usage And Synthesis |
| General Description | This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. (provided by RefSeq) | | Biochem/physiol Actions | PANK2 acts as a key regulatory enzyme in coenzyme A biosynthesis. Mutation in the gene is associated with the development of neurodegeneration with brain iron accumulation (NBIA). |
| | Anti-MLL4 Preparation Products And Raw materials |
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