- Amino-PEG5-COOtBu
-
- $0.00 / 1g
-
2024-03-23
- CAS:1446282-18-3
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
|
| Amino-PEG5-t-butyl ester Basic information |
Product Name: | Amino-PEG5-t-butyl ester | Synonyms: | H2N-PEG5-CH2CH2COOtBu;NH2-PEG5-CH2CH2COOtBu;Amino-PEG5-t-butyl ester;4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-amino-, 1,1-dimethylethyl ester;Amino-PEG5-Boc;tert-butyl 1-amino-3,6,9,12,15-pentaoxaoctadecan-18-oate;Amino-PEG5-COOtBu;Amino-PEG5-t-Bu Ester | CAS: | 1446282-18-3 | MF: | C17H35NO7 | MW: | 365.46 | EINECS: | | Product Categories: | peg | Mol File: | 1446282-18-3.mol | ![Amino-PEG5-t-butyl ester Structure](CAS/20180713/GIF/1446282-18-3.gif) |
| Amino-PEG5-t-butyl ester Chemical Properties |
Boiling point | 439.1±40.0 °C(Predicted) | density | 1.049±0.06 g/cm3(Predicted) | storage temp. | -20°C | solubility | Soluble in Water, DMSO, DCM, DMF | pka | 8.74±0.10(Predicted) | form | viscous liquid | color | Light yellowish |
| Amino-PEG5-t-butyl ester Usage And Synthesis |
Description | Amino-PEG5-t-butyl ester is a PEG molecule consisting of an amino group and a t-butyl protected carboxyl group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.The hydrophilic PEG spacer increases solubility in aqueous media. | Uses | This heterobifunctional, PEGylated crosslinker features an amino group at one end and t-butyl-protected carboxyl group at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Amino-PEG5-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation. |
| Amino-PEG5-t-butyl ester Preparation Products And Raw materials |
|