25-DESACETYL RIFAMPICIN manufacturers
- Rifampicin impurities3
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- $0.00 / 5mg
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2024-12-30
- CAS:16783-99-6
- Min. Order: 5mg
- Purity: 95%+
- Supply Ability: 1000mg
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| | 25-DESACETYL RIFAMPICIN Basic information |
| | 25-DESACETYL RIFAMPICIN Chemical Properties |
| Melting point | >300°C | | Boiling point | 943.1±65.0 °C(Predicted) | | density | 1.35±0.1 g/cm3(Predicted) | | storage temp. | Amber Vial, -20°C Freezer, Under Inert Atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 4.96±0.70(Predicted) | | color | Dark Red to Black | | Stability: | Light Sensitive | | InChIKey | KUJZTIJOBQNKDR-ACYBWPGYNA-N |
| | 25-DESACETYL RIFAMPICIN Usage And Synthesis |
| Description | 25-desacetyl rifampicin, also known as 25-deacetyl-rifampicin, is the main metabolite of rifampicin. It has partial activity. Rifampicin mainly treats various forms of tuberculosis. High-Performance Liquid Chromatographic can be used to determine the metabolism of rifampicin in the body by checking the concentration of 25-desacetyl rifampicin in the urine or blood of tuberculosis patients[1-3]. | | Chemical Properties | Dark Red Solid | | Uses | A metabolite of Rifampicin. | | References | [1]Chik Z, et al. A bioequivalence comparison of two formulations of rifampicin (300- vs 150-mg capsules): An open-label, randomized, two-treatment, two-way crossover study in healthy volunteers. Clinical Therapeutics, 2011.
[2] Mohan B, et al.Evaluation of the recently reported USP gradient HPLC method for analysis of anti-tuberculosis drugs for its ability to resolve degradation products of rifampicin. Journal of Pharmaceutical and Biomedical Analysis, 2003; 31: 607-612.
[3] Lily, et al. The influence of mutation gene rpoB of Mycobacterium tuberculosis cluster I (507-534) on the elimination 25-desacetyl rifampicin in urine of tuberculosis subjects. IOP Conference Series: Earth and Environmental Science, 2018; 1755-1315. |
| | 25-DESACETYL RIFAMPICIN Preparation Products And Raw materials |
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