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Product Name:Tauro-β-muricholic Acid (sodium salt) CAS:145022-92-0 Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Tauro--muricholic Acid (sodium salt) Basic information |
Product Name: | Tauro--muricholic Acid (sodium salt) | Synonyms: | Tauro-β-muricholic acid sodium;T-βMCA sodium;Tauro-β-muricholic Acid sodium salt;Tauro-β-muricholic acid sodium;T-βMCA sodium;2-[[(3α,5β,6β,7β)-3,6,7-trihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonicacid,monosodiumsalt | CAS: | 145022-92-0 | MF: | C26H46NNaO7S | MW: | 539.7 | EINECS: | | Product Categories: | | Mol File: | 145022-92-0.mol | ![Tauro--muricholic Acid (sodium salt) Structure](CAS/20211123/GIF/145022-92-0.gif) |
| Tauro--muricholic Acid (sodium salt) Chemical Properties |
Melting point | 120-125oC | storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere | solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) | form | Solid | color | White to Pale Beige | Stability: | Hygroscopic |
| Tauro--muricholic Acid (sodium salt) Usage And Synthesis |
Description | Tauro-β-muricholic acid (TβMCA) is a competitive and reversible antagonist of the farnesoid X receptor (FXR; IC50 = 40 μM) and a taurine-conjugated form of the murine-specific primary bile acid β-muricholic acid . TβMCA accumulates in germ-free mice under normal conditions but is reduced after colonization with feces from a human donor. TβMCA is increased in the intestines of mice resistant to high-fat diet-induced obesity, fatty liver, and diabetes. | Uses | Tauro-β-muricholic Acid Sodium Salt is the salt form of Tauro-α-muricholic Acid which is a bile acid released by the liver and is typically used in cholestasis studies. |
| Tauro--muricholic Acid (sodium salt) Preparation Products And Raw materials |
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