Company Name: |
J & K SCIENTIFIC LTD.
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Tel: |
010-82848833 400-666-7788 |
Email: |
jkinfo@jkchemical.com |
Products Intro: |
Product Name:(+/-)-BAY-K-8644 CAS:93468-89-4 Purity:>98% Package:5mg, 25mg
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Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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Tel: |
821-50328103-801 18930552037 |
Email: |
3bsc@sina.com |
Products Intro: |
Product Name:(+/-)-BAY K 8644 CAS:93468-89-4 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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Company Name: |
ShangHai Biochempartner Co.,Ltd
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Tel: |
177-54423994 17754423994 |
Email: |
2853530910@QQ.com |
Products Intro: |
Product Name:(+/-)-BAY K 8644 CAS:93468-89-4 Purity:98% HPLC LCMS Package:100MG;1G
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| (+/-)-BAY K 8644 Basic information |
Product Name: | (+/-)-BAY K 8644 | Synonyms: | 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2'-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID METHYL ESTER;1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID, METHYL ESTER;1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-[TRIFLUOROMETHYL]PHENYL)PYRIDINE-3-CARBOXYLIC ACID METHYL ESTER;(+/-)-BAY K 8644;BAY K-8644 (+/-);(+)-(S)-1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl)pyridine-5-carboxylic acid;(±)-Bay K 8644 - CAS 93468-89-4 - Calbiochem | CAS: | 93468-89-4 | MF: | C16H15F3N2O4 | MW: | 356.3 | EINECS: | | Product Categories: | | Mol File: | 93468-89-4.mol | |
| (+/-)-BAY K 8644 Chemical Properties |
Melting point | 166-172 °C | storage temp. | 2-8°C | solubility | DMSO: 184 mg/mL | form | Yellow solid |
Hazard Codes | Xi | Risk Statements | 36/38 | Safety Statements | 26-36 | WGK Germany | 3 |
| (+/-)-BAY K 8644 Usage And Synthesis |
Definition | ChEBI: Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate is a pentasubstituted dihydropyridine carrying methoxycarbonyl, 2-(trifluoromethyl)phenyl and nitro substituents at positions 3, 4 and 5 respectively as well as two methyl substituents at positions 2 and 6. It is a dihydropyridine, a methyl ester, a C-nitro compound and a member of (trifluoromethyl)benzenes. | General Description | Synthetic dihydropyridine derivative that acts as an active Ca2+ slow channel agonist in neuroendocrine, muscle, thyroid and other cell types. Prolongs single channel open time without affecting the close time. An L-type Ca2+ channel agonist. Composed of two optical isomers. The (-)-enantiomer has strong vasoconstrictive, positive inotropic, and Ca2+ agonistic properties, whereas the (+)-enantiomer has weakly vasodilating, negative inotropic, and Ca2+ antagonistic properties. The net effect of the racemic mix is that of the negative enantiomer. Promotes β-cell proliferation/regeneration. | Biochem/physiol Actions | Primary TargetL-type Ca2+ channel |
| (+/-)-BAY K 8644 Preparation Products And Raw materials |
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