- TRANS-ACONITIC ACID
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- $1.00 / 1KG
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2024-07-26
- CAS:4023-65-8
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100000KG
- TRANS-ACONITIC ACID
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- $0.00 / 25KG
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2023-09-01
- CAS:4023-65-8
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
- TRANS-ACONITIC ACID
-
- $0.00 / 25KG
-
2023-09-01
- CAS:4023-65-8
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
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| TRANS-ACONITIC ACID Basic information |
Product Name: | TRANS-ACONITIC ACID | Synonyms: | 1,2,3-PROPENETRICARBOXYLIC ACID;AKOS NCG1-0088;ACONITIC ACID, TRANS-;3-CARBOXY-PENT-2-ENEDIOIC ACID;(E)-3-CARBOXY-PENT-2-ENEDIOIC ACID;PROPENE-TRANS-1,2,3-TRICARBOXYLIC ACID;TRANS-1-PROPENE-1,2,3-TRICARBOXYLIC ACID;TRANS-1,2,3-PROPENETRICARBOXYLIC ACID | CAS: | 4023-65-8 | MF: | C6H6O6 | MW: | 174.11 | EINECS: | 223-688-6 | Product Categories: | antibiotic;monomer | Mol File: | 4023-65-8.mol | ![TRANS-ACONITIC ACID Structure](CAS/GIF/4023-65-8.gif) |
| TRANS-ACONITIC ACID Chemical Properties |
Melting point | 190 °C (dec.)(lit.) | Boiling point | 225.05°C (rough estimate) | density | 0.56 g/cm3 (20℃) | refractive index | 1.5860 (estimate) | FEMA | 2010 | ACONITIC ACID | storage temp. | Store below +30°C. | solubility | 400g/l | form | Solid | pka | 2.8(at 25℃) | color | White to Off-White | PH | 3.14(1 mM solution);2.48(10 mM solution);1.92(100 mM solution) | Odor | at 100.00 %. vegetable musty nut dry toasted | Odor Type | vegetable | Water Solubility | Soluble in water at 20°C 400g/L. Slightly soluble in ether. | BRN | 1725830 | LogP | -0.14 | CAS DataBase Reference | 4023-65-8(CAS DataBase Reference) | EPA Substance Registry System | 1-Propene-1,2,3-tricarboxylic acid, (1E)- (4023-65-8) |
| TRANS-ACONITIC ACID Usage And Synthesis |
Chemical Properties | WHITE TO OFF-WHITE CRYSTALLINE POWDER | Uses | It plays an important role as an antimicrobial agent that blocks the transformation of Leishmania donovani amastigotes to prostigotes. trans-Aconitic acid is also used in synthesis of aconitate esters. It may be used for cross-linking polyvinyl alcohol film for preparing composite nanofiltration membranes. | Definition | ChEBI: The trans-isomer of aconitic acid. | General Description | trans-Aconitic acid is inhibitor of the tricarboxylic acid cycle and was identified in range grasses. | Biochem/physiol Actions | Antimicrobial agent that blocks the transformation of Leishmania donovani amastigotes to prostigotes. | Purification Methods | Purify trans-acid by dissolving it in AcOH (77g/150mL), filtering and cooling. The acid separates (55g) as colourless needles. A further quantity (10g) can be obtained by reducing the volume of the filtrate. The acid is dried in air then in a vacuum desiccator over NaOH. The acid can be recrystallised from Me2CO/CHCl3. The highest melting point is obtained with the very dry acid. A melting point of 209o was obtained on a Dennis bar [Dennis & Shalton J Am Chem Soc 52 3128 1930, Bruce Org Synth Coll Vol II 12 1943]. [Beilstein 2 IV 2405.] |
| TRANS-ACONITIC ACID Preparation Products And Raw materials |
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