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| | Dolutegravir Impurity 16 Basic information |
| Product Name: | Dolutegravir Impurity 16 | | Synonyms: | (4S,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1,2:4,5]pyrazino[2,1-b][1,3];Dolutegravir Impurity 43;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4S,12aS)-;Dolutegravir 4-Epimer;Dolutegravir Impurity 16;(4R,12aS)-N-(2,3-difluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3, 4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3] oxazine-9-carboxamide;(4R,12aS)-N-(3,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4, 6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine9-carboxamide;(4S,12aS)-N-[(2,4-Difluorophenyl)methyl]- 3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8- dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide | | CAS: | 1357289-37-2 | | MF: | C20H19F2N3O5 | | MW: | 419.38 | | EINECS: | | | Product Categories: | | | Mol File: | 1357289-37-2.mol |  |
| | Dolutegravir Impurity 16 Chemical Properties |
| Boiling point | 669.0±55.0 °C(Predicted) | | density | 1.53±0.1 g/cm3(Predicted) | | pka | 4.50±1.00(Predicted) |
| | Dolutegravir Impurity 16 Usage And Synthesis |
| Uses | 4-epi-Dolutegravir, is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. |
| | Dolutegravir Impurity 16 Preparation Products And Raw materials |
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