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Dolutegravir Impurity 16

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CAS:1357289-37-2
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CAS:1357289-37-2
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CAS:1357289-37-2
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CAS:1357289-37-2
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Dolutegravir Impurity 16 Basic information
Product Name:Dolutegravir Impurity 16
Synonyms:Dolutegravir Impurity 16;Dolutegravir 4-Epimer;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4S,12aS)-;Dolutegravir Impurity 43;(4S,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1,2:4,5]pyrazino[2,1-b][1,3];(4R,12aS)-N-(2,3-difluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3, 4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3] oxazine-9-carboxamide;(4R,12aS)-N-(3,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4, 6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine9-carboxamide;(4S,12aS)-N-[(2,4-Difluorophenyl)methyl]- 3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8- dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
CAS:1357289-37-2
MF:C20H19F2N3O5
MW:419.38
EINECS:
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Mol File:1357289-37-2.mol
Dolutegravir Impurity 16 Structure
Dolutegravir Impurity 16 Chemical Properties
Boiling point 669.0±55.0 °C(Predicted)
density 1.53±0.1 g/cm3(Predicted)
pka4.50±1.00(Predicted)
Safety Information
MSDS Information
Dolutegravir Impurity 16 Usage And Synthesis
Uses4-epi-Dolutegravir, is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor.
Dolutegravir Impurity 16 Preparation Products And Raw materials
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