- Fmoc-L-Orn(Boc)-OH
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- $0.00 / 1kg
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2024-11-22
- CAS:109425-55-0
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1T+
Related articles - The uses of Fmoc-Orn(Boc)-OH
- Fmoc-Orn(Boc)-OH is an ornithine-containing amino acid building block. It has been used to conjugate ornithine to GFP-labeled ....
- Mar 28，2024
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| | Fmoc-Orn(Boc)-OH Basic information |
| Product Name: | Fmoc-Orn(Boc)-OH | | Synonyms: | N-DELTA-BOC-N-ALPHA-FMOC-L-ORNITHINE;RARECHEM EM WB 0176;N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-GAMMA-T-BUTYL-OXYCARBONYL-L-ORNITHINE;N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-DELTA-TERT-BUTYLOXYCARBONYL-L-ORNITHINE;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-DELTA-T-BUTOXYCARBONYL-L-ORNITHINE;N-ALPHA-FMOC-N-DELTA-BOC-L-ORNITHINE;N-ALPHA-FMOC-N-DELTA-T-BOC-L-ORNITHINE;N-ALPHA-FMOC-N-DELTA-T-BUTYLOXYCARBONYL-L-ORNITHINE | | CAS: | 109425-55-0 | | MF: | C25H30N2O6 | | MW: | 454.52 | | EINECS: | | | Product Categories: | Ornithine [Org];Fmoc-Amino Acids and Derivatives;Fmoc-Amino acid series;Amino Acids | | Mol File: | 109425-55-0.mol |  |
| | Fmoc-Orn(Boc)-OH Chemical Properties |
| Melting point | 111-115℃ | | Boiling point | 679.0±55.0 °C(Predicted) | | density | 1.226±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | soluble in Methanol | | form | powder to crystal | | pka | 3.85±0.21(Predicted) | | color | White to Almost white | | BRN | 4772025 | | InChIKey | JOOIZTMAHNLNHE-NRFANRHFSA-N | | SMILES | C(O)(=O)[C@H](CCCNC(OC(C)(C)C)=O)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O | | CAS DataBase Reference | 109425-55-0(CAS DataBase Reference) |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29242990 |
| | Fmoc-Orn(Boc)-OH Usage And Synthesis |
| Description | Fmoc-Orn(Boc)-OH is an ornithine-containing amino acid building block. It has been used to conjugate ornithine to GFP-labeled peptides, enhancing cell permeability when compared to unconjugated GFP-labeled peptides. This compound is useful in preparing cyclic peptides and special arginine derivates. | | Chemical Properties | White powder | | Uses | Fmoc-Orn(Boc)-OH is a biochemical reagent. It can be used as a biomaterial or organic compound in life science-related research. | | Preparation | 2 mmol L-Orn was weighted and dissolved in 15 ml of acetonitrile; 16 mmol Boc2O was dissolved in acetonitrile and added dropwise to an acetonitrile solution of ornithine, to react and generate a complex; 10 ml 20% sodium bicarbonate aqueous solution was added, and 2 g of anhydrous sodium carbonate and an appropriate amount of 8-hydroxyquinoline were added in batches; the mixture was stirred and reacted at room temperature for 4 hours to remove copper ions in the complex; then 2 mmol Fmoc-OSu was added to the aforesaid solution, followed by stirring at room temperature for 2 hours; the resultant was recrystallized with an ethyl acetate/petroleum ether mixed solvent, to obtain a peptide head intermediate Fmoc-Orn(Boc)-OH.
 | | reaction suitability | Reaction type: Fmoc solid-phase peptide synthesis | | Solubility in organics | DMF: 20 mg/ml, DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml, DMSO: 10 mg/ml, Ethanol: 10 mg/ml |
| | Fmoc-Orn(Boc)-OH Preparation Products And Raw materials |
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