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Methenamine hippurate

Methenamine hippurate Suppliers list
Company Name: Shanghai Daken Advanced Materials Co.,Ltd
Tel: +86-371-66670886
Email: info@dakenam.com
Products Intro: Product Name:Methenamine hippurate
CAS:5714-73-8
Purity:99% Package:100g ;1KG ;5KG 25KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512
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Products Intro: Product Name:Methenamine hippurate
CAS:5714-73-8
Purity:99% Package:25KG;5KG;1KG
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
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Products Intro: Product Name:Methenamine Hippurate
CAS:5714-73-8
Purity:99.72% Package:100mg;30USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Career Henan Chemica Co
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Products Intro: Product Name:Methenamine hippurate
CAS:5714-73-8
Purity:0.99summer Package:5KG;1KG Remarks:Summer 618
Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250
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Products Intro: Product Name:Methenamine hippurate
CAS:5714-73-8
Purity:99.9% Package:1g;1.1USD Remarks:FDA GMP CEP Approved Manufacturer

Methenamine hippurate manufacturers

  • Methenamine Hippurate
  • Methenamine Hippurate pictures
  • $30.00 / 100mg
  • 2024-11-19
  • CAS:5714-73-8
  • Min. Order:
  • Purity: 99.72%
  • Supply Ability: 10g
  • Methenamine hippurate
  • Methenamine hippurate pictures
  • $0.00 / 1KG
  • 2020-05-04
  • CAS:5714-73-8
  • Min. Order: 1KG
  • Purity: 99.0%
  • Supply Ability: 600 Tons
Methenamine hippurate Basic information
Product Name:Methenamine hippurate
Synonyms:N-benzoylglycine, compound with 1,3,5,7-tetraazatricyclo[3.3.1.13,7]decane (1:1);METHENAMINEHIPPURATE,USP;N-Benzoylglycine 1,3,5,7-tetraazatricyclo[3.3.1.1(3,7)]decane (1:1);Hexamethylentetramine monohippurate;Methenamine hippurate;Methinamine hippurate(USP);glycine,n-benzoyl-,compd.with1,3,5,7-tetraazatricyclo(3.3.1.1(sup3,7))de;haiprex
CAS:5714-73-8
MF:C15H21N5O3
MW:319.37
EINECS:227-206-5
Product Categories:Pharmaceuticals;Intermediates & Fine Chemicals;Heterocycles
Mol File:5714-73-8.mol
Methenamine hippurate Structure
Methenamine hippurate Chemical Properties
Melting point 89-95°C
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
Safety Information
HS Code 2933690000
MSDS Information
Methenamine hippurate Usage And Synthesis
DescriptionMethenamine hippurate is a broad-spectrum urinary antiseptic agent. Under acidic conditions, methenamine hippurate is hydrolyzed to formaldehyde and ammonia, which exerts an antibacterial effect. It is effective against a wide range of bacteria but lacks activity against Proteus and other bacteria that increase urine alkalinity. Formulations containing methenamine hippurate have been used to treat urinary tract infections.
Chemical PropertiesWhite Solid
OriginatorHiprex ,Merrell National,US,1967
UsesAntibacterial (urinary).
DefinitionChEBI: Methenamine hippurate is a N-acylglycine. It is functionally related to a N-benzoylglycine.
Manufacturing Process179 g (1 mol) hippuric acid (benzoyl glycine) and 140 g (1 mol) hexamethylenetetramine were heated under reflux in 500 ml methanol. The small amount of water necessary to give a clear, homogeneous solution was added to the resulting reaction mixture which was then evaporated to dryness. The residue soon crystallized, a procedure that could be greatly accelerated by seeding with crystals of hexamethylenetetramine hippurate from a previous preparation. The resulting solid product was broken up and pulverized. Hexamethylenetetramine hippurate is stable on exposure to air and is soluble in water and alcohol. It melts at 105° to 110°C.
Brand nameUrex(Vatring).
Therapeutic FunctionAntibacterial (urinary)
General DescriptionMethenamine hippurate (Hiprex) is the hippuric acid salt ofmethenamine. It is readily absorbed after oral administrationand is concentrated in the urinary bladder, where it exerts itsantibacterial activity. Its activity is increased in acid urine.
Clinical UseAntibacterial agent
Drug interactionsPotentially hazardous interactions with other drugs
Antibacterials: increased risk of crystalluria with sulphonamides.
Diuretics: effects antagonised by acetazolamide.
MetabolismUnder acid conditions methenamine is slowly hydrolysed to formaldehyde and ammonia. Almost no hydrolysis of methenamine takes place at physiological pH, and it is therefore virtually inactive in the body. Methenamine is rapidly and almost completely eliminated in the urine, and provided this is acidic (preferably below pH 5.5) bactericidal concentrations of formaldehyde occur. Because of the time taken for hydrolysis, however, these do not occur until the urine reaches the bladder.
Methenamine hippurate Preparation Products And Raw materials
Raw materialsHexamethylenetetramine-->Hippuric acid
Tag:Methenamine hippurate(5714-73-8) Related Product Information
Benzhydrylamine Dacarbazine Mefenacet HIPPURIC ACID SODIUM SALT ZOXAMIDE Phenylmethylsulfonyl fluoride Decane 4-Hydroxy-D-(-)-2-phenylglycine Hippuric acid Hexamethylphosphoramide Hexamethylenetetramine Uric acid Methenamine hippurate