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| 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Basic information |
Product Name: | 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID | Synonyms: | 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID;2,2'-(1,2-Ethenediyl)bis(5-isothiocyanatobenzenesulfonic acid);4,4'-Bis(isothiocyanato)stilbene-2,2'-bissulfonic acid;4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic acid;4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid;4,4′-Diisotbiocyano-2,2′-stilbenedisulfnic Acid Disodium Salt;Benzenesulfonic acid,2,2'-(1,2-ethenediyl)bis[5-isothiocyanato-;4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid | CAS: | 53005-05-3 | MF: | C16H10N2O6S4 | MW: | 454.52 | EINECS: | | Product Categories: | Cross Linking Reagents;Fluorescent Labels & Indicators | Mol File: | 53005-05-3.mol | ![4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Structure](CAS/GIF/53005-05-3.gif) |
| 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Chemical Properties |
Melting point | >400°C | density | 1.54±0.1 g/cm3(Predicted) | pka | -1.32±0.50(Predicted) |
HazardClass | IRRITANT-HARMFUL |
| 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Usage And Synthesis |
Chemical Properties | Yellow Crystalline Solid | Uses | Stilbene disulfonates have been employed to inhibit anion transport in a large number of mammalian cell types (GABA, Cl-). Some stilbene disulfonates can bind specifically to proteins that are not anion transporters. DIDS reacts with CD4 glycoprot | Uses | Ion channel inhibitor; especially of anion transport. | Definition | ChEBI: 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid is an arenesulfonic acid. | General Description | Binds covalently and irreversibly to the outer surface of human erythrocyte membranes. Inhibits ATP transport into endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl– uptake (IC50 = 150 nM) in neuroblastoma cells. Has anti-ulcerous properties. | Biochem/physiol Actions | Primary TargetCl- uptake |
| 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Preparation Products And Raw materials |
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