- Norgestrel
-
- $0.00 / 50g
-
2024-11-21
- CAS:6533-00-2
- Min. Order: 50g
- Purity: 98%-102%;USP
- Supply Ability: 10KG
- Norgestrel
-
- $70.00 / 500mg
-
2024-11-19
- CAS:6533-00-2
- Min. Order:
- Purity: 99.91%
- Supply Ability: 10g
- Norgestrel
-
- $1.10 / 1g
-
2024-04-17
- CAS:6533-00-2
- Min. Order: 1g
- Purity: 99.0% min
- Supply Ability: 100 tons min
|
| | Norgestrel Basic information |
| | Norgestrel Chemical Properties |
| Melting point | 239-241 °C(lit.) | | Boiling point | 392.36°C (rough estimate) | | density | 1.0697 (rough estimate) | | refractive index | 1.4900 (estimate) | | storage temp. | 2-8°C | | solubility | Chloroform (Slightly, Sonicated), Dichloromethane (Slightly), Methanol (Slightly) | | form | Solid | | pka | 13.09±0.40(Predicted) | | color | Crystals from diethyl ether-hexane | | InChIKey | WWYNJERNGUHSAO-XUDSTZEESA-N | | CAS DataBase Reference | 6533-00-2(CAS DataBase Reference) | | EPA Substance Registry System | Norgestrel (6533-00-2) |
| | Norgestrel Usage And Synthesis |
| Description | Norgestrel is a synthetic progestin and a racemic mixture of dextronorgestrel and levonorgestrel , of which levonorgestrel is the biologically active component. In vivo, norgestrel administered via intrauterine device (IUD) prevents pregnancy in rats. Formulations containing nogestrel have been used as contraceptives. | | Chemical Properties | White Solid | | Uses | It is an excellent progestational and ovulation inhibiting steroid. The bioactive enantiomer is levorotatory. Progestogen; oral contraceptive. | | Uses | A metabolite of Norgestrel. | | Uses | analgesic, antipyretic | | Uses | Progestogen; oral contraceptive. The bioactive enantiomer is levorotatory | | Uses | An intermediate to the glucuronide metabolite of Levonorgestrel. | | Uses | Protected D-(-)-Norgestrel | | Uses | A glucuronide metabolite of Levonorgestrel. | | Definition | ChEBI: Levonorgestrel is a 17beta-hydroxy steroid, a 3-oxo-Delta(4) steroid and a terminal acetylenic compound. It has a role as a contraceptive drug, a progestin, a synthetic oral contraceptive and a female contraceptive drug. It is functionally related to a norgestrel. It is an enantiomer of a dexonorgestrel. | | Brand name | Ovrette (Wyeth). | | General Description | Norgestrel, (17α)-(±)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one, and levonorgestrel, (17α)-(-)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one,have a C13 ethyl group instead of the C13 methyl but haveprogestational properties similar to those of norethindrone,with decreased androgenic effects. The ethyl group apparentlyprovides unfavorable steric interactions with the ARthat reduce the affinity compared with that with the PRs.Norgestrel is a racemic mixture, while levonorgestrel is thesingle active levorotatory enantiomer. Norgestrel is usedonly in oral contraceptives. Levonorgestrel is used in bothoral combination birth control products and polymeric implantsthat provide contraception for up to 5 years. | | Safety Profile | Human reproductive effects byingestion and implant: menstrual cycle changes ordisorders and female fertility index changes. Anexperimental teratogen. Experimental reproductiveeffects. Questionable carcinogen with experimentalneoplastigenic data. An o |
| | Norgestrel Preparation Products And Raw materials |
|