- Triheptanoin
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- $0.00 / 1KG
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2025-04-15
- CAS:620-67-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 500000kg
- TRIHEPTANOIN
-
- $0.00 / 1KG
-
2025-04-04
- CAS:620-67-7
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1ton
- Triheptanoin
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- $20.00 / 1kg
-
2025-03-07
- CAS:620-67-7
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 20 tons
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- Oct 28，2019
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| | TRIHEPTANOIN Basic information |
| | TRIHEPTANOIN Chemical Properties |
| Boiling point | 200 °C(Press: 1 Torr) | | density | 0.966 g/mL at 20 °C(lit.) | | refractive index | n20/D 1.444 | | storage temp. | Store at -20°C, protect from light | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml | | form | A liquid | | color | Colorless to light yellow | | Stability: | Stable. Incompatible with strong oxidizing agents. | | LogP | 8.86 at 22℃ | | CAS DataBase Reference | 620-67-7 | | EPA Substance Registry System | Heptanoic acid, 1,1',1''-(1,2,3-propanetriyl) ester (620-67-7) |
| Hazard Codes | Xi | | Risk Statements | 38 | | WGK Germany | 1 | | RTECS | MB2660000 | | Toxicity | LD50 intravenous in mouse: 320mg/kg |
| | TRIHEPTANOIN Usage And Synthesis |
| Chemical Properties | colourless liquid | | Uses | triheptanoin is a triglyceride that acts as a surfactant and skinconditioning agent, it also helps increase product viscosity. often used in cleansers, face and neck products, moisturizers and lipsticks. | | Flammability and Explosibility | Non flammable | | Biological Activity | Triheptanoin is a triglyceride with 3 molar eq. of saturated heptanoic acid (C7:0). The even-chain FA does not occur naturally and is able to bypass metabolic block induced by enzyme deficiency and to replenish reduced tricarboxylic acid/TCA-cycle (Krebs cycle or citric acid cycle/CAC) intermediates (anaplerosis) in vivo. | | in vivo | In long-chain fatty acid oxidation disorders (LC-FAOD), Triheptanoin is used as an anaplerotic compound, acting as a source of calories and fatty acids to bypass the LC-FAOD enzyme deficiencies[1].
Triheptanoin can be used for the research of ataxia-telangiectasia (A-T)[2].
Triheptanoin functions as an anaplerotic agent replenishing tricarboxylic acid (TCA) cycle intermediates by metabolism to heptanoate (C7) and subsequently acetyl-CoA and propionyl-CoA that feed into the TCA cycle to supply energy[2].
Triheptanoin mitigates brain ATP depletion and mitochondrial dysfunction, including respiration and redox balance in a mouse model of Alzheimer's disease, supporting the energy failure hypothesis for that disorder[2].
Triheptanoin (Mice were treated with Triheptanoin (35E%) for 10 days prior to pilocarpine injection to induce status epilepticus) preserved mitochondrial functions in the hippocampal formations of pilocarpine-induced status epilepticus (SE) mice[3]. | Animal Model: | 7-8 week old male CD1 (35-40 g)[3] | | Dosage: | 35E% oral Triheptanoin was mixed into mouse chow | | Administration: | Given 35E% Triheptanoin treatment 10 days prior to SE induction | | Result: | Preserved mitochondrial functions in SE mice. |
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| | TRIHEPTANOIN Preparation Products And Raw materials |
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