| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:sn-ET-18-OCH3
CAS:70641-51-9
Purity:>95% Package:5mg, 25mg
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| Company Name: |
Chemsky (shanghai) International Co.,Ltd
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| Tel: |
021-50135380 |
| Email: |
shchemsky@sina.com |
| Products Intro: |
Product Name:1-O-Octadecyl-2-O-Methyl-rac-glycero-3-phosphocholine;Edelfosine, ALP, Ro 14-5243, ET-18-OMe, ET 18-OCH3, NSC 324368, NSC 343649
CAS:70641-51-9
Purity:99% Package:25.0Mg
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| Company Name: |
Synchem OHG
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| Tel: |
+49 5662 408730 |
| Email: |
info@synchem.de |
| Products Intro: |
Product Name:Edelfosine;3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide
CAS:70641-51-9
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| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Edelfosine
CAS:70641-51-9
Purity:>=95% (HPLC) Package:25MG Remarks:SML0332-25MG
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| | 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Basic information |
| | 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Chemical Properties |
| storage temp. | -20°C | | solubility | ethanol: 15 mg/mL at 45 °C, soluble | | form | waxy solid | | color | white | | Water Solubility | Soluble to 20 mM in water |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | YK0718000 |
| | 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Usage And Synthesis |
| Uses | Edelfosine has been used to treat human lung carcinoma A549 cells and study its effects on tuftelin 1 (TUFT1) expression. It is also used to evaluate the cell growth of MCF-7/M cells. | | Definition | ChEBI: 1-octadecyl-2-methylglycero-3-phosphocholine is a glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively. | | General Description | Edelfosine has anti-inflammatory, anti-autoimmune, antiparasitic and anti-viral properties. It stimulates eryptosis by cell shrinkage and cell membrane scrambling. | | Biochem/physiol Actions | Edelfosine is a synthetic alkyl-lisophospholipid with anti-tumor activity. The compound induces apoptosis in a variety of cancer cells. Edelfosine accumulates in the cell membrane, where it alters lipid composition and induces the co-clustering of lipid rafts and Fas/CD95 death receptor. | | storage | Store at -20°C |
| | 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Preparation Products And Raw materials |
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