转铁蛋白受体结合肽
中文名称 | 转铁蛋白受体结合肽 |
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中文同义词 | 转铁蛋白受体结合肽 |
英文名称 | L-Proline, L-threonyl-L-histidyl-L-arginyl-L-prolyl-L-prolyl-L-methionyl-L-tryptophyl-L-seryl-L-prolyl-L-valyl-L-tryptophyl- |
英文同义词 | L-Proline, L-threonyl-L-histidyl-L-arginyl-L-prolyl-L-prolyl-L-methionyl-L-tryptophyl-L-seryl-L-prolyl-L-valyl-L-tryptophyl-;TfR-T12 |
CAS号 | 344618-30-0 |
分子式 | C71H99N19O15S |
分子量 | 1490.73 |
EINECS号 | |
相关类别 | 定制多肽 |
Mol文件 | 344618-30-0.mol |
结构式 | ![]() |
转铁蛋白受体结合肽 性质
密度 | 1.53±0.1 g/cm3(Predicted) |
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酸度系数(pKa) | 3.42±0.20(Predicted) |
TfR-T12 binds to the TfR and is subsequently internalized into TfR-expressing cells.
TfR-T12 is a synthetic peptide obtained by phage display, and is able to bind a different site on TfRs compared with transferrin. TfR-T12 can be chemically conjugated with a pegylated lipid derivative, 3-(N-succinimidyloxyglutaryl)aminopropyl- polyethyleneglycol(2000)- carbamyl distearoyl phosphatidylethanolamine (NHS-PEG2000-DSPE), and used as a functional material to construct the multifunctional lipid vesicles.