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2,4-Dichlorotoluene

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CAS:95-73-8
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2,4-Dichlorotoluene Basic information
Product Name:2,4-Dichlorotoluene
Synonyms:Benzene,2,4-dichloro-1-methyl-;Toluene, 2,4-dichloro-;2,4-DICHLOROTOLUENE;2,4-DICHLOROMETHYLBENZENE;1,3-DICHLORO-4-METHYLBENZENE;2,4-dichloro-1-methyl-benzen;2,4-dichloro-toluen;toluene,2,4-dichloro-
CAS:95-73-8
MF:C7H6Cl2
MW:161.03
EINECS:202-445-8
Product Categories:Pesticides intermediate;Building Blocks;Chemical Synthesis;Halogenated Hydrocarbons;Organic Building Blocks;Aryl;C7;Halogenated Hydrocarbons;Organics
Mol File:95-73-8.mol
2,4-Dichlorotoluene Structure
2,4-Dichlorotoluene Chemical Properties
Melting point -14 °C
Boiling point 200 °C (lit.)
density 1.246 g/mL at 25 °C (lit.)
vapor pressure 4 hPa (50 °C)
refractive index n20/D 1.546(lit.)
Fp 175 °F
storage temp. Store below +30°C.
form Liquid
color Clear colorless
Water Solubility immiscible
BRN 1931691
CAS DataBase Reference95-73-8(CAS DataBase Reference)
NIST Chemistry ReferenceBenzene, 2,4-dichloro-1-methyl-(95-73-8)
EPA Substance Registry System2,4-Dichlorotoluene (95-73-8)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 23-24/25
RIDADR UN 2810
WGK Germany 2
RTECS XT0730000
Autoignition Temperature>450 °C
Hazard Note Harmful
TSCA Yes
HazardClass 9
PackingGroup III
HS Code 29036990
Hazardous Substances Data95-73-8(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: 2400 mg/kg
MSDS Information
ProviderLanguage
2,4-Dichloro-1-methylbenzene English
SigmaAldrich English
ACROS English
ALFA English
2,4-Dichlorotoluene Usage And Synthesis
Chemical PropertiesIt is a clear colorless liquid that is insoluble in water but can be mixed with ethanol, ether, and benzene. It is primarily used as a pesticide and pharmaceutical intermediate, but also serves as a solvent.
Uses2,4-Dichlorotoluene was used as an oxidant and a solvent during anaerobic catalytic oxidation of secondary alcohols by using an in situ (N-heterocyclic carbene)-Ni(0) system. It was used as growth supplement in the culture media of Ralstonia sp. strain PS12. It was used to develop a sensitive method based on solid-phase microextraction followed by gas chromatography-tandem mass spectrometry for the analysis of chlorotoluenes in water samples.
Preparation2,4-Dichlorotoluene is synthesized by diazotization and chlorination with 2,4-diaminotoluene as raw material. First, hydrochloric acid and water into the reaction pot, heated to 50°C, stirring under the dissolution of 2,4-diaminotoluene, then hydrochloric acid and cuprous chloride into the pot, the 1% sodium nitrite solution evenly added, the temperature is maintained at about 60°C, resting stratification, the lower layer of crude product washed with water to neutral, add alkali to alkaline, and then water to remove the alkali, divided 2,4-dichlorotoluene crude product, water distillation of finished products.
DefinitionChEBI: 2,4-Dichlorotoluene is a dichlorobenzene.
Synthesis Reference(s)Tetrahedron Letters, 32, p. 2759, 1991 DOI: 10.1016/0040-4039(91)85078-J
General DescriptionClear colorless liquid.
Air & Water ReactionsInsoluble in water.
Reactivity ProfileSimple aromatic halogenated organic compounds, such as 2,4-Dichlorotoluene, are very unreactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Materials in this group may be incompatible with strong oxidizing and reducing agents. Also, they may be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.
Purification MethodsRecrystallise 2,4-dichlorotoluene from EtOH at low temperature or fractionally distil it. [Beilstein 5 IV 815.]
Tag:2,4-Dichlorotoluene(95-73-8) Related Product Information
Xylene p-Toluenesulfonic acid 1,2-Dichloroethane 2',4'-Dichloroacetophenone 2,4-Dichlorophenol 2,4-Dichlorobenzoic acid Dichloroethane 2,4-Dichlorobenzaldehyde 2',3',4'-TRICHLOROACETOPHENONE 2,4-Dichlorobenzyl alcohol 2,4-Dichlorobenzyl chloride ALPHA,ALPHA-DICHLOROTOLUENE (BENZAL CHLORIDE),α,α-dichlorotoluene benzylidene chloride benzal chloride 1,2-Dichloro-4-(chloromethyl)benzene 3,5-DICHLOROTOLUENE, 98+% 3,4-DICHLOROTOLUENE OEKANAL, 250 MG,3,4-Dichlorotoluene97%,3,4-Dichlorotoluene,98% 2,6-DICHLOROTOLUENE, 99+%,2,6-DICHLOROTOLUENE OEKANAL, 250 MG Toluene 2,3-DICHLOROTOLUENE,2,3-DICHLOROTOLUENE OEKANAL, 250 MG,2,3-DICHLOROTOLUENE 98+%