Iothalamate meglumine

Iothalamate meglumine Suppliers list
Company Name: Shaanxi Dideu Medichem Co. Ltd
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Products Intro: Product Name:Iothalamate meglumine USP/EP/BP
CAS:13087-53-1
Purity:99.9% Package:25kgs/Drum;200kgs/Drum Remarks:FDA GMP CEP Approved Manufacturer
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Products Intro: Product Name:MEGLUMINE IOTALAMATE
CAS:13087-53-1
Purity:98%+ Package:Standard or custom package Remarks:excellent quality and reliable supplier
Company Name: TargetMol Chemicals Inc.
Tel:
Email: support@targetmol.com
Products Intro: Product Name:Iothalamate meglumine;EINECS 235-998-9;Cysto-Conray;Methylglucamine iotalamate;Meglumine conray
CAS:13087-53-1
Package:100 mg;500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: TargetMol Chemicals Inc.
Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Products Intro: Product Name:Iothalamate meglumine
CAS:13087-53-1
Package:50mg;1980USD|100mg;2500USD|25mg;1520USD
Company Name: Shandong Ono Chemical Co., Ltd.  
Tel: 0539-6362799 20)
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Products Intro: CAS:13087-53-1
Purity:99% Package:25g;100g;250g;500g;25Kg

Iothalamate meglumine manufacturers

Iothalamate meglumine Basic information
Product Name:Iothalamate meglumine
Synonyms:Iothalamate Meglumine;D-Glucitol, 1-deoxy-1-(methylamino)-, 3-(acetylamino)-2,4,6-triiodo- 5-[(methylamino)carbonyl]benzoate (salt);1-deoxy-1-(methylamino)-D-glucitol 3-(acetylamino)-2,4,6-triiodo-5-[(methylamino)carbonyl]benzoate;N-Methylglucamine salt;iothalamic acid meglumine salt;Iothalamic acid·meglumine;Meglumine iotalamate;Meglumine iothalamate injection
CAS:13087-53-1
MF:C11H9I3N2O4.C7H17NO5
MW:809.115
EINECS:2359989
Product Categories:Organics
Mol File:13087-53-1.mol
Iothalamate meglumine Structure
Iothalamate meglumine Chemical Properties
Safety Information
MSDS Information
Iothalamate meglumine Usage And Synthesis
OriginatorConray,Mallinckrodt Inc.,US,1962
UsesDiagnostic aid (radiopaque medium).
DefinitionChEBI: Iothalamate meglumine is an amidobenzoic acid.
Manufacturing ProcessCrude 5-amino-2,4,6-triiodo-N-methylisophthalamic acid (21.0 g) was dissolved in warm dimethylacetamide (40 ml) and acetic anhydride (30 ml) and concentrated sulfuric acid (2 drops) were added. This solution was heated on the steam bath for 2 hours, then heated at 110°C for 5 minutes, then cooled. Water and ammonium hydroxide were added to destroy the excess acetic anhydride, after which the mixture was evaporated to a volume of 50 ml. The cooled solution was acidified with concentrated hydrochloric acid and a tan solid was collected. The crude product was dissolved in 100 ml of water containing a slight excess of sodium hydroxide. The pH was adjusted to 4.5 with acetic acid, and the solution was treated with charcoal. The colorless solution was acidified with concentrated hydrochloric acid and cooled, and the precipitate was filtered off and dried under reduced pressure. The resulting 5- acetamido-2,4,6-triiodo-N-methylisophthalamic acid decomposes about 285°C and does not melt below 300°C.
5-acetamido-2,4,6-triiodo-N-methylisophthalamic acid was slurried in water and dissolved by the addition of an equivalent quantity of N-methylglucamine. The solution was evaporated to dryness to yield the meglumate salt of 5- acetamido-2,4,6-triiodo-N-methylisophthalamic acid.
Brand nameConray(Mallinckrodt).
Therapeutic FunctionDiagnostic aid (radiopaque medium)
General DescriptionIothalamate meglumineis a high-osmolar, ionic monomer with 47% boundiodine content. Conray is indicated for use in angiography,excretory urography, arthrography, cholangiography, endoscopicretrograde cholangiopancreatography, and variousCT procedures.
Iothalamate meglumine Preparation Products And Raw materials
Raw materialsAcetic anhydride-->5-Amino-2,4,6-triiodoisophthalic acid-->Meglumine
Tag:Iothalamate meglumine(13087-53-1) Related Product Information
Closantel Glucosamine Cyclic adenosine monophosphate Meglumine Iotalamic acid 5-AMINO-N-METHYLISOPHTHALAMIC ACID 2-IODO-5-METHYLBENZOIC ACID 2-IODO-3-METHYLBENZOIC ACID D-Glucammonium, N-(3-acetamido-5-(methylcarbamoyl)-2,4,6-triiodobenzyl )-N-(2,3-dihydroxypropyl)-N-methyl-, (3-acetamido-5-methylcarbamoyl-2, 4,6-triiodo)-, benzoate 4-IODO-3-METHYLBENZOIC ACID 5-Amino-2,4,6-triiodo-N-methylisophthalamic Acid Iothalamate meglumine