MYOMODULIN A TRIFLUOROACETATE SALT
| 中文名称 | MYOMODULIN A TRIFLUOROACETATE SALT |
|---|---|
| 中文同义词 | 肌调蛋白A;肌调蛋白;MYOMODULIN A三氟乙酸盐;H-LEU-ARG-LEU-MET-SER-MET-PRO-OH;化合物MYOMODULIN;肌调蛋白片段多肽;(S)-N-((5S,8S,11S,14S,17S,20S)-20-胺甲酰基-17-(3-胍基丙基)-8-(羟甲基)-14-异丁基-22-甲基-11-(2-(甲基硫基)乙基)-6,9,12,15,18-五氧代-2-硫代-7,10,13,16,19-五氮杂TR二十烷-5-基)吡咯烷-2-甲酰胺 |
| 英文名称 | MYOMODULIN |
| 英文同义词 | L-Pro-L-Met-L-Ser-L-Met-L-Leu-L-Arg-L-Leu-NH2;Myomodulin A;Myomodulin【Aplysi】;Myomodulin【Aplysia california】;MYOMODULIN A TRIFLUOROACETATE SALT ≥98%;L-Prolyl-L-methionyl-L-seryl-L-methionyl-L-leucyl-L-arginyl-L-leucinamide;Myomodulin A (Aplysia californica clone pMM12);Myomodulin A (Aplysia kurodai) |
| CAS号 | 110570-93-9 |
| 分子式 | C36H67N11O8S2 |
| 分子量 | 846.12 |
| EINECS号 | |
| 相关类别 | 生化试剂;多肽;Invertebrate Neuropeptides;Neuropeptides;Peptides for Cell Biology;其他生化试剂 |
| Mol文件 | 110570-93-9.mol |
| 结构式 |  |
MYOMODULIN A TRIFLUOROACETATE SALT 性质
| 密度 | 1.38±0.1 g/cm3(Predicted) |
|---|---|
| 储存条件 | −20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | 12.79±0.46(Predicted) |
Myomodulin decreases period and increases spike frequency in oscillator heart interneurons. Myomodulin enhances the hyperpolarization-activated cation current and inhibits the electrogenic Na/K pump. A myomodulin peptide has been suggested to mediate the response of the giant glial cells to stimulation of the Leydig interneuron in the central nervous system of the leech Hirudo medicinalis. The peptide evokes a membrane outward current (EC 50 approximately 2 μM), which neither desensitizes nor shows any sign of run-down, and elicits a K + conductance increase of the glial cell membrane. Myomodulin modulate ion channels in a wide variety of organisms including Aplysia, Lymnaea, and Pleurobranchaea. Myomodulin differentially modulates the potassium currents and reduces the amplitude of the Ca 2+ current by 20%.