MRTX-1719 manufacturers
- MRTX-1719
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- $8.00 / 1kg
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2024-04-24
- CAS:2630904-45-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| MRTX-1719 Basic information |
Product Name: | MRTX-1719 | Synonyms: | Benzonitrile, 2-[4-[4-(aminomethyl)-1,2-dihydro-1-oxo-6-phthalazinyl]-1-methyl-1H-pyrazol-5-yl]-4-chloro-6-(cyclopropyloxy)-3-fluoro-, (2R)-;MRTX-1719,CRC,Histone Methyltransferase,NSCLC,Inhibitor,MTA,MRTX1719,MRTX 1719,inhibit,PRMT5;2-[4-[4-(Aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl]-1-methyl-5-pyrazolyl]-4-chloro-6-cyclopropoxy-3-fluorobenzonitrile;(2R)-2-(4-(4-(Aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl)-1-methyl-1H-pyrazol-5-yl)-4-chloro-6-cyclopropoxy-3-fluorobenzonitrile | CAS: | 2630904-45-7 | MF: | C23H18ClFN6O2 | MW: | 464.89 | EINECS: | | Product Categories: | | Mol File: | 2630904-45-7.mol | ![MRTX-1719 Structure](CAS/20211123/GIF/2630904-45-7.gif) |
| MRTX-1719 Chemical Properties |
density | 1.58±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | form | Solid | pka | 11.37±0.40(Predicted) | color | White to light yellow |
| MRTX-1719 Usage And Synthesis |
Biological Activity | MRTX-1719 is a potent first-in-class selective inhibitor of the PRMT5/MTA complex, with an IC50 of less than 10 nM in PRMT5/MTA MTAPDEL SDMA cells[1]. | References | [1]. Targeting the genetic and immunological drivers of cancer. |
| MRTX-1719 Preparation Products And Raw materials |
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