| Company Name: |
MedChemexpress LLC
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021-58955995 |
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sales@medchemexpress.cn |
| Products Intro: |
Product Name:Dopropidil
CAS:79700-61-1
Purity:300RMB/1mg Package:>98%
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Dopropidil manufacturers
- Dopropidil
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- $1980.00 / 50mg
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2024-10-28
- CAS:79700-61-1
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | Dopropidil Basic information |
| Product Name: | Dopropidil | | Synonyms: | Dopropidil;4205CERM;Pyrrolidine, 1-[1-[(2-methylpropoxy)methyl]-2-[[1-(1-propyn-1-yl)cyclohexyl]oxy]ethyl]- | | CAS: | 79700-61-1 | | MF: | C20H35NO2 | | MW: | 321.501 | | EINECS: | | | Product Categories: | | | Mol File: | 79700-61-1.mol |  |
| | Dopropidil Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| | Dopropidil Usage And Synthesis |
| Uses | Dopropidil is a novel anti-anginal calcium ion modulating agent, possessing intracellular calcium antagonist activity and
anti-ischemic effects in several predictive animal models. | | in vivo | Dopropidil (1 and 2.5 mg/kg) dose-dependently reduces the electrical (ST segment elevation), biochemical (lactate production and potassium release), and mechanical (loss in myocardial segment contractility) perturbations induced by ischemia in the anesthetized dog. Intraduodenal administration of Dopropidil (50 mg/kg) significantly reduces isoproterenol-induced tachycardia. This effect is manifest at 15-120 min following administration of the compound which indicates a rapid absorption and a long duration of action. In conscious dogs Dopropidil (12-14 mg/kg p.o.) reduces resting heart rate by approximately10 beats/min[1]. | | References | [1] J. Planellas, et al. Dopropidil, A Novel Antianginal Calcium Modulating Agent. Cardiovascular Drug Reviews. Vol.12, No.3, pp. 208-224. |
| | Dopropidil Preparation Products And Raw materials |
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