Company Name: |
Leancare Ltd.
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Tel: |
+33 962096793 |
Email: |
enquiry@leancare.co.uk |
Products Intro: |
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Company Name: |
2A PharmaChem USA
|
Tel: |
(630) 737-0988 |
Email: |
sales@2apharmachem.com |
Products Intro: |
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| Zocainone Basic information |
| Zocainone Chemical Properties |
| Zocainone Usage And Synthesis |
Originator | Zocainone,ZYF Pharm Chemical | Manufacturing Process | 21.0 g of N,N-diethylaminoethyl chloride are added drop by drop to 35.0 g of
the sodium salt of 3-o-hydroxyphenoxy-4-phenyl-3-butene-2-one suspended
in 600 ml of anhydrous acetone. The mixture is heated under reflux for 4 h,
the sodium chloride is filtered off, and the filtrate is evaporated to dryness.
The residue is dissolved in water and extracted a number of times with diethyl
ether. The ether phase, after drying over Na 2 SO 4 , is evaporated to dryness
and purified by distillation in a bulb apparatus, and 3-[o-(β-N,N-
diethylaminoethoxy)phenoxy]-4-phenyl-3-buten-2-one was obtained, boiling
point 200-210°C/0.6 mm Hg). | Therapeutic Function | Antiarrhythmic |
| Zocainone Preparation Products And Raw materials |
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