| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Purity:affinity isolated antibody, lyophilized powder Remarks:clone 3A12, purified immunoglobulin, buffered aqueous solution
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| Company Name: |
Vision BioSystems
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| Tel: |
800 753 7264 |
| Email: |
sales.usa@vision-bio.com |
| Products Intro: |
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| | ANTI-GHR Basic information |
| Product Name: | ANTI-GHR | | Synonyms: | ANTI-GHR;ANTI-GROWTH HORMONE RECEPTOR;Anti-Growth Hormone Receptor antibody produced in goat;Monoclonal Anti-GHR antibody produced in mouse;Anti-GHBP;Anti-GHR antibody produced in rabbit | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-GHR Structure]() |
| | ANTI-GHR Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder |
| | ANTI-GHR Usage And Synthesis |
| General Description | This gene encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. The precise location of this cleavage site has not been determined for the human protein |
| | ANTI-GHR Preparation Products And Raw materials |
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