Company Name: |
TargetMol Chemicals Inc.
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Tel: |
4008200310 |
Email: |
marketing@tsbiochem.com |
Products Intro: |
Product Name:Butopamine;Butopamine CAS:66734-12-1 Purity:98% Package:5 mg
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| Butopamine Basic information |
Product Name: | Butopamine | Synonyms: | (R)-4-Hydroxy-α-[[(R)-3-(4-hydroxyphenyl)-1-methylpropylamino]methyl]benzyl alcohol;4-[(R)-3-[[(R)-2-(4-Hydroxyphenyl)-2-hydroxyethyl]amino]butyl]phenol;Compound LY-131126;LY-131126;Butopamine;Benzenemethanol, 4-hydroxy-α-[[[(1R)-3-(4-hydroxyphenyl)-1-methylpropyl]amino]methyl]-, (αR)- | CAS: | 66734-12-1 | MF: | C18H23NO3 | MW: | 301.38 | EINECS: | | Product Categories: | | Mol File: | 66734-12-1.mol | |
| Butopamine Chemical Properties |
Boiling point | 520.5±50.0 °C(Predicted) | density | 1.189±0.06 g/cm3(Predicted) | pka | 9.97±0.26(Predicted) |
| Butopamine Usage And Synthesis |
Originator | Butopamine,ZYF Pharm Chemical | Definition | ChEBI: A 4-(1-hydroxy-2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)phenol in which both stereocentres have R configuration. It is the most active of the four diastereoisomers that make up the animal feed additive ractopamine. | Manufacturing Process | A solution of 32.8 g (0.2 m) of methyl 2-(4-hydroxyphenyl)ethyl ketone and
42.6 g (0.2 m) of 1-(4-hydroxyphenyl)-2-aminoethanol in 380 ml of ethanol containing 3.8 g of 5% palladium on carbon was stirred for 16 h at 60°C
under hydrogen at 55 psi. The reaction mixture was then filtered, and the
filtrate was diluted by addition of 350 ml of water. The aqueous mixture was
concentrated to a volume of about 400 ml, and then washed with
dichloromethane. The aqueous mixture was acidified by addition of 50 ml of conc. hydrochloric
acid. After standing at room temperature for 2 h, the aqueous acid mixture
was filtered and the filter cake was washed with 40 ml of ice water and dried
at 50°C in vacuum to provide 47.0 g of 1-(4-hydroxyphenyl-2-
propylamino]ethanol hydrochloride, melting point 124-129°C. The 1-(4-hydroxyphenyl)-2-[1-methyl-3-(4-hydroxyphenyl)propylamino]
ethanol was obtained by treatment of 1-(4-hydroxyphenyl-2-
propylamino]ethanol hydrochloride with sodium hydroxide. | Therapeutic Function | Cardiotonic |
| Butopamine Preparation Products And Raw materials |
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