| Company Name: |
Guangzhou Isun Pharmaceutical Co., Ltd
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| Tel: |
020-39119399 18927568969 |
| Email: |
isunpharm@qq.com |
| Products Intro: |
Product Name:proglumide sodium
CAS:99247-33-3
Purity:98% Package:1G; 5G; 25G; 100G; 1KG; 5KG
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PROGLUMIDE, SODIUM SALT manufacturers
- Proglumide sodium
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- $198.00 / 50mg
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2024-10-24
- CAS:99247-33-3
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | PROGLUMIDE, SODIUM SALT Basic information |
| Product Name: | PROGLUMIDE, SODIUM SALT | | Synonyms: | DL-4-(BENZOYLAMINO)-5-(DIPROPYLAMINO)-5-OXOPENTANOIC ACID, NA;4-BENZOYLAMINO-5-DIPROPYLAMINO-5-OXOPENTANOIC ACID SODIUM;PROGLUMIDE SODIUM;PROGLUMIDE, SODIUM SALT;4-benzamido-n,n-dipropyl-,sodiumsalt,dl-glutaramicaci;dl-4-benzamido-n,n-dipropylglutaramicacidsodiumsalt;pentanoicacid,4-(benzoylamino)-5-(dipropylamino)-5-oxo-,monosodiumsalt,(;PROGLUMIDE SODIUM SALT SELECTIVE CHOLECY STOK | | CAS: | 99247-33-3 | | MF: | C18H27N2NaO4 | | MW: | 358.41 | | EINECS: | | | Product Categories: | | | Mol File: | 99247-33-3.mol |  |
| | PROGLUMIDE, SODIUM SALT Chemical Properties |
| storage temp. | Desiccate at RT | | solubility | H2O: soluble | | form | solid | | color | white | | Water Solubility | Soluble to 100 mM in water |
| | PROGLUMIDE, SODIUM SALT Usage And Synthesis |
| Uses | Proglumide sodium salt has been used to study the effects of proglumide on macronutrient selection in European sea bass Dicentrarchus labrax, L. | | Biochem/physiol Actions | Proglumide sodium salt is a non-peptide cholecystokinin receptor antagonist that has greater selectivity for the CCKA subtype. It selectively blocks central nervous system effects. Proglumide sodium salt is orally active. | | in vivo | Proglumide (250-750 mg/kg; intraperitoneal injection; adult male Sprague Dawley rats) treatment is significantly effective in ameliorating the seizure activities, cognitive dysfunctions, and cerebral oxidative stress[1]. | Animal Model: | Adult male Sprague Dawley rats (200-250?g; 2 months old) are induced status epilepticus (SE)[1] | | Dosage: | 250 mg/kg, 500 mg/kg, and 750?mg/kg | | Administration: | Intraperitoneal injection | | Result: | Dose-dependently and significantly increased the latencies to seizure and SE. Significantly and dose-dependently attenuated Li-PC (SE) induced increase in thiobarbituric acid (TBARS) and catalase (CAT), attenuated Li-Pc induced decrease in SOD, and attenuated depletion of GSH and glutathione-S transferase (GST) in the hippocampus and striatum.
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| | storage | Desiccate at RT |
| | PROGLUMIDE, SODIUM SALT Preparation Products And Raw materials |
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