- N-Methylisatoic anhydride
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- $0.00 / 1KG
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2022-01-04
- CAS:10328-92-4
- Min. Order: 1g
- Purity: 98%minHPLC
- Supply Ability: 500kgs/month
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| N-methylisatoic anhydride Basic information |
Product Name: | N-methylisatoic anhydride | Synonyms: | N-methyl isotoic anhydride;Isatoic anhydride, N-Methyl-;N-Methylisatioc anhydride;1-methyl-1H-benzo[d][1,3]oxazine-2,4-dione;1-Methyl-1,2-dihydro-4H-3,1-benzoxazine-2,4-dione;1-Methyl-1H-3,1-benzoxazine-2,4-dione;1-Methyl-4H-3,1-benzoxazine-2(1H),4-dione;N-Methylisatoic anhydride,90%,tech. | CAS: | 10328-92-4 | MF: | C9H7NO3 | MW: | 177.16 | EINECS: | 233-714-8 | Product Categories: | Monomers;Polymer Science;pharmacetical;Anhydride Monomers | Mol File: | 10328-92-4.mol | ![N-methylisatoic anhydride Structure](CAS/GIF/10328-92-4.gif) |
| N-methylisatoic anhydride Chemical Properties |
Melting point | 165 °C (dec.)(lit.) | Boiling point | 309.06°C (rough estimate) | density | 1.3312 (rough estimate) | vapor density | 6.1 (vs air) | refractive index | 1.5200 (estimate) | storage temp. | Inert atmosphere,Room Temperature | solubility | Soluble in DMSO | form | Solid | pka | -2.24±0.20(Predicted) | color | White to yellow | Sensitive | Moisture Sensitive | CAS DataBase Reference | 10328-92-4(CAS DataBase Reference) | EPA Substance Registry System | 2H-3,1-Benzoxazine-2,4(1H)-dione, 1-methyl- (10328-92-4) |
Hazard Codes | Xi | Risk Statements | 36/37/38 | Safety Statements | 26-37/39 | WGK Germany | 3 | RTECS | DM3140000 | TSCA | Yes | HS Code | 2934.99.4400 |
| N-methylisatoic anhydride Usage And Synthesis |
Chemical Properties | brownish chunks | Uses | N-Methylisatoic anhydride is a 2'-OH selective acylation agent of RNAs, and is widely used for resolving secondary RNA structures using the SHAPE (Selective 2'-Hydroxyl Acylation Analyzed by Primer Extension) technology. | Definition | ChEBI: N-methylisatoic anhydride is a 3,1-benzoxazin-1,4-dione having an N-methyl substituent. | Application | N-Methylisatoic anhydride was first condensed with ethanolamine to give N-(2-hydroxyethyl)-2-methylaminobenzamide. Cyclization of the latter with ethyl pyruvate gave quinazoline derivatives which, upon hydrolysis and dehydrative cyclization with l-methyl-2-chloropyridinium iodide, afforded the l,4-oxazines[3,4-]quinazoline. |
| N-methylisatoic anhydride Preparation Products And Raw materials |
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