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Products Intro: |
Product Name:Bamaluzole CAS:87034-87-5 Purity:98% Package:5mg;10mg;20mg;50mg;100mg;200mg
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| Bamaluzole Basic information |
Product Name: | Bamaluzole | Synonyms: | Bamaluzole;4-(2-chlorobenzyloxy)-1-methyl-1H-imidazo[4,5-c]pyridine;1H-Imidazo[4,5-c]pyridine, 4-[(2-chlorophenyl)methoxy]-1-methyl- | CAS: | 87034-87-5 | MF: | C14H12ClN3O | MW: | 273.72 | EINECS: | | Product Categories: | | Mol File: | 87034-87-5.mol | |
| Bamaluzole Chemical Properties |
storage temp. | Store at -20°C | solubility | Soluble in DMSO |
| Bamaluzole Usage And Synthesis |
Originator | Bamaluzole,Onbio Inc. | Uses | Bamaluzole, is a GABA receptor agonist. | Manufacturing Process | 1-Chlorophenyl-2-methanol is dissolved in dimethylformamide; NaH is added
and the mixture is stirred at 20°C for 1 h. After a solution of 4-chloro-1-
methyl-1H-imidazo[4,5-c]pyridine [melting point 132°-134°C; obtainable by
reaction of 4-methylamino-3-nitropyridine with HCl/SnCl2 to give 3-amino-2-
chloro-4-methylaminopyridine (melting point 170°-173°C) and reaction with
HCOOH/acetic anhydride] in dimethylformamide has been added, the mixture
is stirred at 90°-95°C for 15 h. The mixture is evaporated and the residue is
worked up in the customary manner to give 4-o-chlorobenzyloxy-1-methyl-
1H-imidazo[4,5-c]pyridine, melting point 132°-135°C (crystallize from ethyl
acetate-tetrahydofuran). | Therapeutic Function | Anticonvulsant |
| Bamaluzole Preparation Products And Raw materials |
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