Log in | Join Free | china | japan | germany
ChemicalBook > Product Catalog >Organic Chemistry >Hydrocarbons and derivatives >Acyclic hydrocarbons >(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane

(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane

Request For Quotation
(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Suppliers list
Company Name: Shanghai Rochi Pharmaceutical Co.,Ltd.
Tel: 21-38751876 +8615000076078
Email: info@rochipharma.com
Products Intro: Product Name:(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
CAS:423165-07-5
Purity:99%min Package:1kg 5kg 10kg 25kg
Company Name: Beijing Mediking Biopharm Co., Ltd
Tel: +undefined15901403431
Email: sales01@mediking.cn
Products Intro: Product Name:(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo [3.2.1]octane
CAS:423165-07-5
Package:25KG;
Company Name: Hebei Yanxi Chemical Co., Ltd.
Tel: +8617531190177
Email: peter@yan-xi.com
Products Intro: Product Name:(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
CAS:423165-07-5
Purity:0.99 Package:1kg Remarks:Factory direct sales
Company Name: Henan Fengda Chemical Co., Ltd
Tel: +86-371-86557731 +86-13613820652
Email: info@fdachem.com
Products Intro: Product Name:(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
CAS:423165-07-5
Purity:99% Package:1KG;101USD|1000KG;1USD
Company Name: Shanghai Daken Advanced Materials Co.,Ltd
Tel: +86-371-66670886
Email: info@dakenam.com
Products Intro: Product Name:(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
CAS:423165-07-5
Purity:99% Package:100g ;1KG ;5KG 25KG

(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane manufacturers
(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Basic information
Product Name:(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
Synonyms:(3-Exo)-3-[3-methyl-5-(1-methylethyl)-4H-1,2,4-triazol-4-yl] -8-Azabicyclo[3.2.1]octane;Des[1-(4,4-difluorocyclohexanecarboxamido)-1-phenylpropyl] Maraviroc;UK 408027;(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane;8-Azabicyclo[3,2,1]octane3-[3-methyl-5-(1-methlethyl)-4H-1,2,4-triazol-4-yl]-, (3-exo)-;Maraviroc Intermediate 2;Maraviroc interMediate(Tropinone);(3-exo)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]octane
CAS:423165-07-5
MF:C13H22N4
MW:234.35
EINECS:1533716-785-6
Product Categories:Chiral Reagents;Metabolites & Impurities
Mol File:423165-07-5.mol
(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Structure
(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Chemical Properties
Melting point 117 ºC
Boiling point 402.4±55.0 °C(Predicted)
density 1.31
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility Chloroform
pka10.71±0.40(Predicted)
form Solid
color Off-White to Pale Yellow
InChIInChI=1/C13H22N4/c1-8(2)13-16-15-9(3)17(13)12-6-10-4-5-11(7-12)14-10/h8,10-12,14H,4-7H2,1-3H3/t10-,11+,12-
InChIKeyCEIRCCADSFHOQD-ZSBIGDGJNA-N
SMILESC(C1=NN=C(C)N1[C@@H]1C[C@H]2CC[C@H](N2)C1)(C)C |&1:7,9,12,r|
Safety Information
HS Code 2933592000
MSDS Information
(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Usage And Synthesis
Chemical PropertiesOff-White to Pale Yellow Solid
UsesA metabolite of Maraviroc.
Synthesis A solution of 8-benzyl-3-(3-isopropyl-5-methyl-[1,2,4]triazol-4-yl)-8-aza-bicyclo[3.2.1]octane (2.0 g, 6.17 mmol) in methanol (30 mL) was treated with 10% palladium on carbon (0.25 g) under a hydrogen atmosphere (50 psi) at ambient temperature, overnight. The mixture was filtered through a pad of Celite and the filtrate was concentrated to give (1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane. Yield: 1.36 g (94%).
(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane Preparation Products And Raw materials
Raw materials8-Benzyl-3-exo-(5-isopropyl-3-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane-->8-BENZYL-1AH,5AH-NORTROPAN-3-ONE OXIME
Tag:(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane(423165-07-5) Related Product Information
Bensulfuron methyl Thiophanate-methyl ISOPROPYL LAURATE Isopropyl alcohol 2,2,4-Trimethylpentane 1-OCTANESULFONIC ACID, SODIUM SALT, MONOHYDRATE N-OCTANE 1-Bromooctane Methyl acrylate Methylparaben Kresoxim-methyl Methyl Methyl bromide 6-ACETHYOXY-8-METHYL-8-AZABICYCLO(3.2.1)OCTAN-3-ONE 2-CARBOMETHOXY-3-TROPINONE (+/-)-exo-6-Hydroxytropinone N-Carbethoxy-4-tropinone N-Boc-Nortropinone