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| 4-FLUOROPHENYLMAGNESIUM BROMIDE Basic information |
Product Name: | 4-FLUOROPHENYLMAGNESIUM BROMIDE | Synonyms: | 4-FLUOROPHENYLMAGNESIUM BROMIDE;4-FLUOROPHENYLMAGNESIUM BROMIDE, 2M IN DIETHYL ETHER;4-FLUOROPHENYLMAGNESIUM BROMIDE, 2.0M SO LUTION IN DIETHYL ETHER;4-FLUOROPHENYLMAGNESIUM BROMIDE SOL., ~2 .0 M IN DIETHYL ET;4-FLUOROPHENYLMAGNESIUM BROMIDE, 1.0M SO LUTION IN TETRAHYDROFURAN;4-FLUOROPHENYLMAGNESIUM BROMIDE SOL., ~1 M IN THF;4-Fluorophenylmagnesium Bromide 1.0 M In Tetrahydrofuran;4-Fluorophenylmagnesium Bromide 2.0 M In Diethyl Ether | CAS: | 352-13-6 | MF: | C6H4BrFMg | MW: | 199.3 | EINECS: | 627-087-3 | Product Categories: | Grignard Reagents;Aryl;Organometallic Reagents;Grignard Reagent | Mol File: | 352-13-6.mol | ![4-FLUOROPHENYLMAGNESIUM BROMIDE Structure](CAS/GIF/352-13-6.gif) |
| 4-FLUOROPHENYLMAGNESIUM BROMIDE Chemical Properties |
Melting point | 5 °C | Boiling point | 66°C | density | 1.043 g/mL at 25 °C | Fp | −40 °F | storage temp. | Flammables + water-Freezer (-20°C)e area | form | Solution | color | Clear yellow to red-brown | Water Solubility | It reacts violently with water. | Sensitive | Air & Moisture Sensitive | BRN | 636802 | InChIKey | QYBFFRXNNFXREA-UHFFFAOYSA-M | CAS DataBase Reference | 352-13-6 | EPA Substance Registry System | Magnesium, bromo(4-fluorophenyl)- (352-13-6) |
| 4-FLUOROPHENYLMAGNESIUM BROMIDE Usage And Synthesis |
Chemical Properties | clear yellow to red-brown solution | Uses | 4-Fluorophenylmagnesium bromide solution (Grignard reagent) can be used as a reagent in the synthesis of:
- Useful key intermediate in the synthesis of paroxetine.
- Arylsulfides via cross-coupling reaction with thiols.
- 4-Arylmethyl-1-phenylpyrazole and 4-aryloxy-1-phenylpyrazole derivatives as androgen receptor antagonists.
- Grignard intermediate for preparing aprepitant.
| Uses | 4-Fluorophenylmagnesium bromide is used as a reagent for the introduction of the 4-Fluorophenyl group. |
| 4-FLUOROPHENYLMAGNESIUM BROMIDE Preparation Products And Raw materials |
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