Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
|
Tel: |
821-50328103-801 18930552037 |
Email: |
3bsc@sina.com |
Products Intro: |
Product Name:PROSTAGLANDIN B1 CAS:13345-51-2 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
|
Company Name: |
Sinopharm Chemical Reagent Co,Ltd.
|
Tel: |
86-21-63210123 |
Email: |
sj_scrc@sinopharm.com |
Products Intro: |
Product Name:Prostaglandin B1 (25 mg) ((13E,15S)-15-Hydroxy-9-oxoprosta-8(12),13-dien-1-oic Acid) CAS:13345-51-2 Package:25 mg
|
|
| PROSTAGLANDIN B1 Basic information |
Product Name: | PROSTAGLANDIN B1 | Synonyms: | (13E,15S)-15-Hydroxy-9-oxoprosta-8(12),13-dien-1-oic acid, PGB1;(-)-(E)-Prostaglandin E1-278;PGE1-278;Prostaglandin E1-278;(+)-2-[(E,R)-3-Hydroxy-1-octenyl]-5-oxo-1-cyclopentene-1-heptanoic acid;[13E,15R,(+)]-15-Hydroxy-9-oxo-8,12-didehydroprost-13-en-1-oic acid;15-epi-PGB1;9-OXO-15S-HYDROXY-PROSTA-8(12),13E-DIEN-1-OIC ACID | CAS: | 13345-51-2 | MF: | C20H32O4 | MW: | 336.47 | EINECS: | 234-237-8 | Product Categories: | | Mol File: | 13345-51-2.mol | |
| PROSTAGLANDIN B1 Chemical Properties |
Melting point | 69-71°C | Boiling point | 531.4±43.0 °C(Predicted) | density | 1.101±0.06 g/cm3(Predicted) | storage temp. | −20°C | solubility | acetone: 20 mg/mL, clear, colorless to very faintly yellow | form | powder | pka | 4.77±0.10(Predicted) | color | white to light yellow | BRN | 2004447 | Stability: | Light Sensitive |
Safety Statements | 22-24/25 | WGK Germany | 3 | F | 8-10 | HS Code | 2937500000 |
| PROSTAGLANDIN B1 Usage And Synthesis |
Uses | Prostaglandin B1 is a novel microbial biopolymer which has been shown to improve the longevity of type 2 diabetic rodents. Oligomers of prostaglandin B1 inhibit arachidonic acid mobilization in human neutrophils and endothelial cells. | Definition | ChEBI: Prostaglandin B1 is a member of the class of prostaglandins B that is prosta-8(12),13-dien-1-oic acid carrying oxo and hydroxy substituents at positions 9 and 15 respectively (the 13E,15S-stereoisomer). It has a role as a human metabolite. It is a conjugate acid of a prostaglandin B1(1-). | Enzyme inhibitor | This eicosanoid (FWB1 (free-acid) = 336.47 g/mol; CAS 13345-51-2, for PGB1,
and 39306-29-1, for Bx) is a metabolite of prostaglandin E1: prostaglandin
Bx is an oligomer of prostaglandin B1. The X-ray crystal structure of
prostaglandin B1 suggests this prostaglandin has an unusual L-shaped
configuration, with the a and w side chains roughly perpendicular to one
another. The 15-hydroxyl group, which is normally directed away from
the centroid of the prostaglandin in the standard hairpin mod+el, is turned
inward in prostaglandin B1. Target (s) : FoF1 ATPase, or H-transporting
two-sector ATPase, inhibited by prostaglandin Bx; 15-
hydroxyprostaglandin dehydrogenase; phospholipase A2, inhibited by
prostaglandin Bx. |
| PROSTAGLANDIN B1 Preparation Products And Raw materials |
|