9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID

9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID Suppliers list
Company Name: Shanghai Hongye Biotechnology Co. Ltd  
Tel: 400-9205774
Email: sales@glpbio.cn
Products Intro: Product Name:CAY10408
CAS:212310-16-2
Purity:>98% Package:1mg;10mg;50mg;100mg;
Company Name: Hangzhou Synstar pharmaceutical Technology CO.,Ltd  
Tel: 0571-85361029
Email: synstar518@163.com
Products Intro: Product Name:CAY10408
CAS:212310-16-2
Purity:0.98 Package:100mg、500mg、1g、5g
Company Name: Jinan ponder chemical co. LTD  
Tel: 0531-0000
Email: thinklifescience@163.com
Products Intro: Product Name:212310-16-2
CAS:212310-16-2
Purity:99% HPLC Package:1KG;500G;100G;50G;1G
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Products Intro: Product Name:CAY10408
CAS:212310-16-2
Purity:98% Package:1mg;5mg;10mg
Company Name: Cayman Chemical Company  
Tel: (800) 364-9897
Email: cayman@caymanchem.com
Products Intro: Product Name:CAY10408
CAS:212310-16-2
Package:>98% Remarks:13747
9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID Basic information
Product Name:9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID
Synonyms:9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID;CAY10408;HJVBXPOYFHMZAS-QTUFFCAPSA-N;5-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,4R)-4-hydroxy-4-(1-propylcyclobutyl)-1-buten-1-yl]-5-oxocyclopentyl]-, (5Z)-
CAS:212310-16-2
MF:C23H36O5
MW:392.53
EINECS:
Product Categories:
Mol File:212310-16-2.mol
9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID Structure
9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID Chemical Properties
solubility DMF: 15 mg/ml; DMSO: 25 mg/ml; Ethanol: 15 mg/ml; PBS (pH 7.2): 3 mg/ml
Safety Information
MSDS Information
9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID Usage And Synthesis
DescriptionButaprost is a structural analog of prostaglandin E2 (PGE2) with good selectivity for the EP2 receptor subtype. Butaprost binds with about 1/10 the affinity of PGE2 to the recombinant murine EP2 receptor, and does not bind appreciably to any of the other murine EP receptors or DP, TP, FP, or IP receptors.1 CAY10408 is a free acid, 2-series analog of butaprost. It is the less active C-16 epimer compared to the 16(S) isomer, which has the same stereochemistry as butaprost. Butaprost has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells.2 Since the majority of reports related to butaprost utilize the methyl ester derivative,3,4 it may be some time before the precise pharmacology of the free acid compounds, like CAY10408, is reported.
References1. Kiriyama, M., Ushikubi, F., Kobayashi, T., et al. Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells Br. J. Pharmacol. 122(2),217-224(1997).
2. Lawrence, R.A., and Jones, R.L. Investigation of the prostaglandin E (EP-) receptor subtype mediating relaxation of the rabbit jugular vein Br. J. Pharmacol. 105,817-824(1992).
3. Regan, J.W., Bailey, T.J., Pepperl, D.J., et al. Cloning of a novel human prostaglandin receptor with characteristics of the pharmacologically defined EP2 subtype Mol. Pharmacol. 46(2),213-220(1994).
4. Talpain, E., Armstrong, R.A., Coleman, R.A., et al. Characterization of the PGE receptor subtype mediating inhibition of superoxide production in human neutrophils Br. J. Pharmacol. 114(7),1459-1465(1995).
9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID Preparation Products And Raw materials
Tag:9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID(212310-16-2) Related Product Information
9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID