Company Name: |
BioBioPha Co., Ltd.
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Tel: |
0871-65217109 13211707573; |
Email: |
y.liu@mail.biobiopha.com |
Products Intro: |
Product Name:Isowighteone CAS:68436-47-5 Purity:96.0% Package:5mg Remarks:BBP01342
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Company Name: |
Wuhan ChemFaces Biochemical Co., Ltd.
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Tel: |
18607101326 15172504745 |
Email: |
aileen@chemfaces.com |
Products Intro: |
Product Name:Isowighteone CAS:68436-47-5 Purity:>=98% Package:5mg ,10mg ,20mg ,50mg ,100mg; 200mg; 500mg or according to customer requirements Remarks:2388/5mg
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| Isowightenon Basic information |
Product Name: | Isowightenon | Synonyms: | 3'-(3-Methyl-2-butenyl)-4',5,7-trihydroxyisoflavone;3'-Dimethylallylgenistein;4',5,7-Trihydroxy-3'-(3-methyl-2-butenyl)isoflavone;4',5,7-Trihydroxy-3'-prenylisoflavone;Isowightenon;Isowighteone;Isowigtheone;4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-[4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl]- | CAS: | 68436-47-5 | MF: | C20H18O5 | MW: | 338.35 | EINECS: | | Product Categories: | | Mol File: | 68436-47-5.mol | |
| Isowightenon Chemical Properties |
solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | form | powder | color | Yellow |
| Isowightenon Usage And Synthesis |
Uses | Isowighteone is a natural product derivative of Genistein (G350000). Genistein exhibits specific inhibitory activity against tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol. | Definition | ChEBI: Isowighteone is a member of the class of 7-hydroxyisoflavones that is isoflavone substituted by hydroxy groups at positions 5, 7 and 4' and a prenyl group at position 3'. It has been isolated from Ficus mucuso. It has a role as a plant metabolite. It is functionally related to an isoflavone. | target | Antifection |
| Isowightenon Preparation Products And Raw materials |
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