N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE manufacturers
- WAY-213613
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- $723.00 / 10mg
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2024-10-24
- CAS:868359-05-1
- Min. Order:
- Purity:
- Supply Ability: 10g
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| N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE Basic information |
Product Name: | N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE | Synonyms: | N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE;WAY 213613;N4-[4-(2-Bromo-4,5-difluorophenoxy)phenyl)]-L-asparagine;(S)-2-amino-4-((4-(2-bromo-4,5-difluorophenoxy)phenyl)amino)-4-oxobutanoic acid;L-Asparagine, N-[4-(2-bromo-4,5-difluorophenoxy)phenyl]-;WAY 213613,WAY213613 | CAS: | 868359-05-1 | MF: | C16H13BrF2N2O4 | MW: | 415.19 | EINECS: | | Product Categories: | | Mol File: | 868359-05-1.mol | |
| N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE Chemical Properties |
Boiling point | 565.6±50.0 °C(Predicted) | density | 1.664±0.06 g/cm3(Predicted) | storage temp. | Desiccate at RT | solubility | DMSO: >10mg/mL | form | white powder | pka | 2.38±0.10(Predicted) | color | White to off-white |
Hazard Codes | Xn | Risk Statements | 22 | RIDADR | UN 2811 6.1 / PGIII | WGK Germany | 3 |
| N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE Usage And Synthesis |
Uses | WAY 213613 is a selective non-substrate inhibitor of EAAT2. It is used in the methods of treating or inhibiting onset of Huntington''s disease with gene modulatory compounds. | Biological Activity | Potent, non-substrate inhibitor of EAAT2 (GLT-1) that displays > 44-fold selectivity over EAAT1 and EAAT3 (IC 50 values are 85, 3787 and 5004 nM for EAAT2, EAAT3 and EAAT1 respectively). Exhibits no activity towards ionotropic and metabotropic glutamate receptors. | storage | Desiccate at RT |
| N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE Preparation Products And Raw materials |
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