| Company Name: |
BOC Sciences
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| Tel: |
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| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:(±)-LY 367385
CAS:198419-90-8
Purity:98% Remarks:(±)-LY367385 is a selective mGlu1a antagonist.
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| Company Name: |
ChemeGen 中国
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:(±)-LY367385
CAS:198419-90-8
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| | (+/-)-LY367385 Basic information |
| Product Name: | (+/-)-LY367385 | | Synonyms: | 4-(AMINO-CARBOXY-METHYL)-3-METHYL-BENZOIC ACID;BENZENEACETIC ACID, A-AMINO-4-CARBOXY-2-METHYL-;LY 367385, (±)-;Benzeneacetic acid, α-amino-4-carboxy-2-methyl-;(+/-)-LY367385 | | CAS: | 198419-90-8 | | MF: | C10H11NO4 | | MW: | 209.2 | | EINECS: | | | Product Categories: | | | Mol File: | 198419-90-8.mol |  |
| | (+/-)-LY367385 Chemical Properties |
| Boiling point | 434.0±45.0 °C(Predicted) | | density | 1.393±0.06 g/cm3(Predicted) | | solubility | Water: 20 mg/ml | | form | A solid | | pka | 1.72±0.10(Predicted) | | color | White to off-white |
| | (+/-)-LY367385 Usage And Synthesis |
| Description | (±)-LY367385 is an antagonist of metabotropic glutamate receptor 1α (mGluR1α).1 It inhibits phosphoinositide (PI) hydrolysis selectively in AV-12 cells expressing mGluR1α over those expressing mGluR5a (IC50s = 19 and >300 μM, respectively). | | References | 1. Salt, T.E., Jones, H.E., Copeland, C.S., et al. Function of mGlu1 receptors in the modulation of nociceptive processing in the thalamus Neuropharmacology 79(100),405-411(2014). |
| | (+/-)-LY367385 Preparation Products And Raw materials |
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