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Benzyl 2-chloroacetate

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Products Intro: Product Name:Benzyl 2-chloroacetate
CAS:140-18-1
Purity:99.0% Package:1KG;|25KG
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Products Intro: Product Name:Benzyl chloroacetate
CAS:140-18-1
Purity:98%(Min,GC) Package:100g;1kg;5kg,10kg,25kg,50kg
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Products Intro: Product Name:Benzyl 2-chloroacetate
CAS:140-18-1
Purity:99% Package:100g ;1KG ;5KG 25KG
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Products Intro: Product Name:Benzyl 2-chloroacetate
CAS:140-18-1
Purity:99% Package:25KG;5KG;1KG
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Products Intro: Product Name:Benzyl chloroacetate
CAS:140-18-1

Benzyl 2-chloroacetate manufacturers

Benzyl 2-chloroacetate Basic information
Product Name:Benzyl 2-chloroacetate
Synonyms:AKOS B029322;CHLOROACETIC ACID BENZYL ESTER;BENZYL-(CHLORACETAT);BENZYL CHLOROACETATE;benzyl 2-chloroacetate;Acetic acid, chloro-, phenylmethyl ester;benzyl chloracetate;Phenylmethyl 2-chloroacetate
CAS:140-18-1
MF:C9H9ClO2
MW:184.62
EINECS:205-400-0
Product Categories:C8 to C9;Carbonyl Compounds;Esters
Mol File:140-18-1.mol
Benzyl 2-chloroacetate Structure
Benzyl 2-chloroacetate Chemical Properties
Boiling point 90 °C/1 mmHg (lit.)
density 1.215 g/mL at 25 °C (lit.)
refractive index n20/D 1.525(lit.)
Fp >230 °F
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form clear liquid
Specific Gravity1.215
color Oil
Water Solubility insoluble
CAS DataBase Reference140-18-1(CAS DataBase Reference)
EPA Substance Registry SystemAcetic acid, chloro-, phenylmethyl ester (140-18-1)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
RTECS AF8750000
HS Code 29154000
ToxicityLDLo ipr-mus: 500 mg/kg CBCCT* 8,99,56
MSDS Information
ProviderLanguage
Benzyl 2-chloroacetate English
SigmaAldrich English
ACROS English
Benzyl 2-chloroacetate Usage And Synthesis
Chemical PropertiesBenzyl 2-chloroacetate is a colorless, slightly viscous liquid. Insoluble in water, soluble in alcohol and oils. Sp.Gr = 1.22. Mild, Jasmin-type odor, floral-fruity, of considerable tenacity.
UsesBenzyl chloroacetate may be used:
  • in the synthesis of monoesters of phosphonoacetic acid
  • in the synthesis of N-benzoyl-glycyl- hydroxyl acetic acid, ester substrate for carboxypeptidase Y catalyzed peptide synthesis
  • as reagent in the total syntheses of the (±)-di-O-methyl ethers of the norlignans sequirin-A, agatharesinol, and hinokiresinol, and of (±)-tri-O-methyl sequirin-E
PreparationFrom Benzyl alcohol and Monochloroacetic acid by direct esterification under azeotropic conditions.
General DescriptionBenzyl chloroacetate is an ester. Could find usc in Jasmin, Lilac. Appleblossom fragrances, particularly for soap, where this ester has greater fixative effect than the Benzyl acetate. However, this ester must be absolutely acid-free to be permitted or recommended for use in any cosmetic product. The acid is highly corrosive. Older odor-descriptions of this ester seem to indicate that the product has not always been very pure.
Safety ProfileModerately toxic byintraperitoneal route. When heated todecomposition it emits toxic fumes of Cl- .
Benzyl 2-chloroacetate Preparation Products And Raw materials
Raw materialsDichloromethane-->Pyridine-->Chloroacetyl chloride-->Benzyl alcohol
Preparation ProductsDiethyl (benzyloxycarbonylmethyl)phosphonate, 98 %
Tag:Benzyl 2-chloroacetate(140-18-1) Related Product Information
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