| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
|
| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:ANTI-ALPHA-ACTININ
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
|
| Company Name: |
Riedel-de Haen AG
|
| Tel: |
800 558-9160 |
| Email: |
|
| Products Intro: |
Purity:whole antiserum Remarks:~1.0 mg/mL, clone CGA7, purified immunoglobulin, buffered aqueous solution
|
| Company Name: |
SIGMA-RBI
|
| Tel: |
800 736 3690 (Orders) |
| Email: |
|
| Products Intro: |
|
| Company Name: |
BD Biosciences
|
| Tel: |
1 877 232 8995 U.S. orders |
| Email: |
|
| Products Intro: |
|
|
| | ANTI-ALPHA-ACTININ Antibody Basic information |
| | ANTI-ALPHA-ACTININ Antibody Chemical Properties |
| Hazard Codes | Xn | | Risk Statements | 21/22 | | Safety Statements | 36/37 | | WGK Germany | 3 |
| | ANTI-ALPHA-ACTININ Antibody Usage And Synthesis |
| Uses | May be used in the study of skeletal muscle organization and in studies of the membrane anchorage sites of actin. | | General Description | α-actinin is a 100kD actin binding protein found in muscle as well as non-muscle cells. In smooth muscle, α-actinin is identified in dense bodies and plaques characteristic of tissues whereas it is associated with z-discs that define muscle sarcomas in normal skeletal muscle. Monoclonal anti-α-actinin antibody can be used in immunoblotting to study the membrane anchorage sites and immunochemical identification of α-actinin. It can also be used in immunofluorescence to study the localization of α-actinin in cultured cells and tissues. Mouse anti-α-actinin antibody reacts specifically with chicken fibroblasts. The product has also shown reactivity for mouse and human cells. | | Biochem/physiol Actions | α?actinin regulates muscle contraction and cytoskeletal organization. It promotes cell migration and acts as an actin crosslinker. Mutations in the α-actinin gene is observed in heterogeneous hypertrophic cardiomyopathy and in juvenile onset atrial fibrillation. |
| | ANTI-ALPHA-ACTININ Antibody Preparation Products And Raw materials |
|